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Leucocyte Typing: Human Leucocyte Differentiation Antigens Detected by Monoclonal Antibodies
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The article was published on 1984-04-01 and is currently open access. It has received 70 citations till now. The article focuses on the topics: Monoclonal antibody & Typing.read more
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Journal ArticleDOI
Antigen CD34+ marrow cells engraft lethally irradiated baboons.
Berenson Rj,Robert G. Andrews,William I. Bensinger,Kalamasz Df,Glenn H. Knitter,C. D. Buckner,Irwin D. Bernstein +6 more
TL;DR: The data suggest that stem cells responsible for hematopoietic reconstitution are CD34+, and these cells are enriched from marrows of five baboons using avidin-biotin immunoadsorption.
Journal ArticleDOI
CD14 : cell surface receptor and differentiation marker
TL;DR: CD14 function, its expression in different cell types and the regulation of expression, including the generation of soluble CD14, are described, and the diagnostic value of CD14 in various diseases is discussed.
Journal ArticleDOI
The skin immune system (SIS): Distribution and immunophenotype of lymphocyte subpopulations in normal human skin
Jan D. Bos,I M Zonneveld,Pranab K. Das,S. R. Krieg,Chris M. van der Loos,Martien L. Kapsenberg +5 more
TL;DR: The results indicate that preferential perivascular localization of activated T lymphocytes is the characteristic of normal human skin, which might be a reflection of continuous antigen recognition upon endothelial cell presentation and/or continuous T cell-mediated endothelialcell activation thereby inducing enhanced antigen clearing by the skin's endothelium.
Journal Article
A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions.
TL;DR: A unique antibody reacting with the alpha-chain of the human leukocyte function-associated Ag-1 is described, which stimulates homotypic cell-cell interactions in a manner very similar to 12-O-tetradecanoyl-phorbol-13-acetate (TPA), in contrast to other anti-LFA-1 mAb which inhibit cell aggregation.
Journal ArticleDOI
Predominance of "memory" T cells (CD4+, CDw29+) over "naive" T cells (CD4+, CD45R+) in both normal and diseased human skin.
TL;DR: The predominant presence of the 4B4+ 2H4- “memory” subpopulation of CD4+ T cells in all diseases studied as well as in normal human skin seems to indicate that the skin immune system is rather unidirectional in its increase in this sub population of the inducer T-cell subset.
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