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Life Out of Sequence: A Data-Driven History of Bioinformatics
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The article was published on 2013-11-04 and is currently open access. It has received 102 citations till now. The article focuses on the topics: Sequence (medicine).read more
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The politics of life itself Biomedicine, power, and subjectivity in the twenty-first century
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The Century of the Gene. Evelyn Fox Keller. Harvard University Press, Cambridge, MA. 2000. pp. 186. Price £15.95, hardback. ISBN 0 674 00372 1.
TL;DR: Genetics Laboratory Investigations is a compilation of practical exercises that form a strong foundation in both classical genetics and more recent molecular genetic techniques for students at degree level and is accompanied by an Instructors Manual that includes hints, sources of materials, and answers to the many questions posed.
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The Anatomy of Medical Research: US and International Comparisons
Hamilton Moses,David H. M. Matheson,Sarah Cairns-Smith,Benjamin P. George,Chase Palisch,Chase Palisch,E. Ray Dorsey +6 more
TL;DR: New investment is required if the clinical value of past scientific discoveries and opportunities to improve care are to be fully realized and the United States will relinquish its historical international lead in the next decade unless such measures are undertaken.
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The real cost of sequencing: scaling computation to keep pace with data generation.
Paul Muir,Shantao Li,Shaoke Lou,Daifeng Wang,Daniel Spakowicz,Leonidas Salichos,Jing Zhang,George M. Weinstock,Farren J. Isaacs,Joel Rozowsky,Mark Gerstein +10 more
TL;DR: As the cost of sequencing continues to decrease and the amount of sequence data generated grows, new paradigms for data storage and analysis are increasingly important.
Molecules as Documents of Evolutionary History
Emile Zuckerkandl,Linus Pauling +1 more
TL;DR: Different types of molecules are discussed in relation to their fitness for providing the basis for a molecular phylogeny, i.e. the different types of macromolecules that carry the genetic information or a very extensive translation thereof.
References
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Outline of a Theory of Practice
TL;DR: Bourdieu as mentioned in this paper develops a theory of practice which is simultaneously a critique of the methods and postures of social science and a general account of how human action should be understood.
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Cluster analysis and display of genome-wide expression patterns
TL;DR: A system of cluster analysis for genome-wide expression data from DNA microarray hybridization is described that uses standard statistical algorithms to arrange genes according to similarity in pattern of gene expression, finding in the budding yeast Saccharomyces cerevisiae that clustering gene expression data groups together efficiently genes of known similar function.
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The Human Genome Browser at UCSC
W. James Kent,Charles W. Sugnet,Terrence S. Furey,Krishna M. Roskin,Tom H. Pringle,Alan M. Zahler,and David Haussler +6 more
TL;DR: A mature web tool for rapid and reliable display of any requested portion of the genome at any scale, together with several dozen aligned annotation tracks, is provided at http://genome.ucsc.edu.
Book
The Origins of Order: Self-Organization and Selection in Evolution
TL;DR: The structure of rugged fitness landscapes and the structure of adaptive landscapes underlying protein evolution, and the architecture of genetic regulatory circuits and its evolution.
and Boundary Objects: Amateurs and Professionals in Berkeley's Museum of Vertebrate Zoology, 1907-39
Susan Leigh,James R. Griesemer +1 more
TL;DR: A model of how one group of actors managed this tension between divergent viewpoints was presented, drawing on the work of amateurs, professionals, administrators and others connected to the Museum of Vertebrate Zoology at the University of California, Berkeley, during its early years.