Journal ArticleDOI
Lithium cyanohydridoborate, a versatile new reagent
Richard F. Borch,H. Dupont Durst +1 more
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This article is published in Journal of the American Chemical Society.The article was published on 1969-07-01. It has received 103 citations till now. The article focuses on the topics: Lithium & Reagent.read more
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Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures1
Ahmed F. Abdel-Magid,Kenneth G. Carson,Bruce D. Harris,and Cynthia A. Maryanoff,Rekha D. Shah +4 more
TL;DR: In the reductive amination of some aldehydes with primary amines where dialkylation is a problem, a stepwise procedure involving imine formation in MeOH followed by reduction with NaBH(4) gave consistently higher yields and fewer side products.
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A Review on the Use of Sodium Triacetoxyborohydride in the Reductive Amination of Ketones and Aldehydes
TL;DR: The reductive amination of aldehydes and ketones is a cornerstone reaction and is one of the most useful and important tools in the synthesis of different kinds of amines as mentioned in this paper.
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NaBH4 reduction of cyclic imides
TL;DR: One of the carbonyl functions of succinimides and glutarimides is selectively reduced by sodium borohydride in presence of hydrochloric acid yielding ω-carbinol-lactams as mentioned in this paper.
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Chemoselective reductive alkylation of ammonia with carbonyl compounds: synthesis of primary and symmetrical secondary amines
TL;DR: In this article, an efficient, general procedure for highly chemoselective reductive mono-alkylation of ammonia with ketones is reported, followed by in situ sodium borohydride reduction, and a straightforward workup afforded primary amines in good yield.
Journal ArticleDOI
Direct and indirect reductive amination of aldehydes and ketones with solid acid-activated sodium borohydride under solvent-free conditions
Byung Tae Cho,Sang Kyu Kang +1 more
TL;DR: In this article, a simple and convenient procedure for reductive amination of aldehydes and ketones using sodium borohydride activated by boric acid, p-toluenesulfonic acid monohydrate or benzoic acid as reducing agent under solvent-free conditions is described.