Journal ArticleDOI
Long-Term Platelet Support of Patients with Aplastic Anemia: Effect of Splenectomy and Steroid Therapy
F C Grumet,R A Yankee +1 more
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This article is published in Annals of Internal Medicine.The article was published on 1970-07-01. It has received 89 citations till now. The article focuses on the topics: Aplastic anemia & Anemia.read more
Citations
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Use of leucocyte‐poor blood components and HLA‐matched‐platelet donors to prevent HLA alloimmunization
TL;DR: Improved methods of removing leucocytes from blood components appear to offer the best approach for minimizing HLA alloimmunization, as the provision of HLA‐matched platelet donors for prophylactic platelet support of all patients is not feasible.
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Selection of unrelated compatible platelet donors by lymphocyte HL-A matching.
TL;DR: Observations indicate that alloimmunization in multi-transfused patients is primarily due to HL-A antigens and that lymphocyte HL- A typing can be used to select unrelated compatible platelet donors for refractory patients.
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Platelet transfusions from HL-A compatible unrelated donors to alloimmunized patients.
TL;DR: Patients needing long-term platelet transfusion support become alloimmunized to transplantation (HL-A) antigens present in random-donor blood products, which results in refractoriness to random donor blood products.
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Salmonella septicemia from platelet transfusions. Study of an outbreak traced to a hematogenous carrier of Salmonella cholerae-suis.
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The Assessment of Drug-Dependent and Isoimmune Antiplatelet Antibodies by the Use of Platelet Aggregometry
TL;DR: Serum derived from patients with idiopathic thromboytopenic purpura did not cause platelet aggregation, and the simple technique of platelet aggregometry may be a useful adjunct in the selection of compatible donors for platelet transfusion.
References
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The quantitative relation between platelet count and hemorrhage in patients with acute leukemia.
TL;DR: In patients with acute leukemia disturbances of the hemostatic mechanism have been described in such patients, including qualitative platelet defects and the presence of a fibrinolytic system and hypofibrinogenemia.
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The Relation of Blood Platelets to Hemorrhagic Disease: Description of a Method for Determining the Bleeding Time and Coagulation Time and Report of Three Cases of Hemorrhagic Disease Relieved by Transfusion
TL;DR: Three cases and experiments are reported which furnish additional evidence to show that the blood platelets play a part in stopping hemorrhage, and that one type of hemorrhagic disease may be attributed to an extreme reduction in the number of platelets.
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Platelet transfusion therapy; the selection of compatible platelet donors for refractory patients by lymphocyte HL-A typing.
TL;DR: HL-A lymphocyte typing of family members can be used to predict platelet compounding in patients with bone-marrow aplasia and revealed that the excellent responses occurred with platelets from HL-A identical siblings.
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Causes of Death in Acute Leukemia: A Ten-Year Study of 414 Patients From 1954-1963.
TL;DR: Major causes of death in acute leukemia were infection in 70% of patients and hemorrhage in 52%.