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Maca (Lepidium meyenii Walp), una revisión sobre sus propiedades biológicas

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TLDR
Results of studies about the effects of maca on sexual function, spermatogenesis, female reproductive function, memory, depression and anxiety, and energy as well as effects on benign prostatic hyperplasia, osteoporosis and metabolic syndrome are summarized.
Abstract
La maca (Lepidium meyenii) es una planta que crece sobre los 4000 metros de altitud en los Andes Centrales del Peru, presenta diferentes variedades de acuerdo al color de su hipocotilo. La presente revision resume los resultados de estudios sobre los efectos de la maca en la funcion sexual, la espermatogenesis, la funcion reproductiva femenina, la memoria, la depresion y la ansiedad, como energizante y contra la hiperplasia benigna de prostata, osteoporosis y sindrome metabolico. Se discute tambien su efecto antienvejecimiento y la seguridad en su consumo. Se han demostrado diferencias en el efecto de las variedades negra, amarilla y roja de maca. La maca negra es la que mejores resultados presenta sobre la espermatogenesis, la memoria y contra la fatiga, mientras que la maca roja es la variedad que mejor revierte la hiperplasia benigna de prostata y la osteoporosis inducida experimentalmente. Ademas, la maca reduce los niveles de glucosa, y su consumo se relaciona con la reduccion de la presion arterial y un mejor puntaje de salud. Estudios experimentales han demostrado que el consumo a corto como a largo plazo no muestra toxicidad tanto in vivo como in vitro. A pesar que los estudios experimentales han demostrado que la maca presenta diversos efectos beneficos, son necesarios mas estudios clinicos para confirmar estos resultados

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Journal ArticleDOI

Is the hype around the reproductive health claims of maca (Lepidium meyenii Walp.) justified

TL;DR: The health claims of maca cannot be fully supported from a scientific standpoint and more research is needed as it appears that the indigenous local knowledge about the health benefits of Maca has been dragged out of context to fit the demands of a growing market for herbal remedies.
Journal ArticleDOI

Chemical profiling analysis of Maca using UHPLC-ESI-Orbitrap MS coupled with UHPLC-ESI-QqQ MS and the neuroprotective study on its active ingredients

TL;DR: The results suggested that Maca from Yunnan province was the potential substitute for the one from Peru, and the inhibition of acetylcholinesterase and butyrylcholiersterase was a possible mechanism of its neuroprotective effect.

Lepidium meyenii ( Maca ) improved semen parameters in adult men

TL;DR: Treatment with Maca resulted in increased seminal volume, sperm count per ejaculum, motile sperm count, and sperm motility by mechanisms not related to LH, FSH, PRL, T and E2.

Effect of Lepidium meyenii (maca) roots on spermatogenesis of male rats

TL;DR: The Lepidium meyenii root invigorates spermatogenesis in male rats by acting on its initial stages (IX-XIV), which includes mitosis and seminiferous tubules.
References
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Journal ArticleDOI

Effect of a lipidic extract from Lepidium meyenii on sexual behavior in mice and rats

TL;DR: Oral administration of M-01 and M-02 enhanced the sexual function of the mice and rats, as evidenced by an increase in the number of complete intromissions and the numberof sperm-positive females in normal mice, and a decrease in the LPE in male rats with erectile dysfunction.
Journal ArticleDOI

Estrogen Receptor-β: Recent Lessons from in Vivo Studies

TL;DR: A clear role for ERβ has been established in the ovary, cardiovascular system, and brain as well as in several animal models of inflammation including arthritis, endometriosis, inflammatory bowel disease, and sepsis.
Journal ArticleDOI

Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men.

TL;DR: Test the hypothesis that Maca has no effect on serum reproductive hormone levels in apparently healthy men when administered in doses used for aphrodisiac and/or fertility-enhancing properties and showed that treatment with Maca does not affect serum reproductive hormones levels.
Journal Article

Lepidium meyenii (Maca) improved semen parameters in adult men.

TL;DR: Treatment with Maca resulted in increased seminal volume, sperm count per ejaculum, motile sperm count, and sperm motility and this was not related to dose of Maca.
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