MR imaging of the fetal brain
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TLDR
The common clinical conditions imaged by fetal MRI as well as recent advances in fetal MRI research are discussed.Abstract:
Fetal MRI is clinically performed to evaluate the brain in cases where an abnormality is detected by prenatal sonography. These most commonly include ventriculomegaly, abnormalities of the corpus callosum, and abnormalities of the posterior fossa. Fetal MRI is also increasingly performed to evaluate fetuses who have normal brain findings on prenatal sonogram but who are at increased risk for neurodevelopmental abnormalities, such as complicated monochorionic twin pregnancies. This paper will briefly discuss the common clinical conditions imaged by fetal MRI as well as recent advances in fetal MRI research.read more
Citations
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Diagnosis and Treatment of Fetal Cardiac Disease A Scientific Statement From the American Heart Association
Mary T. Donofrio,Anita J. Moon-Grady,Lisa K. Hornberger,Joshua A. Copel,Mark Sklansky,Alfred Abuhamad,Bettina F. Cuneo,James C. Huhta,Richard A. Jonas,Anita Krishnan,Stephanie Lacey,Wesley Lee,Erik C. Michelfelder,Gwen R. Rempel,Norman H. Silverman,Thomas L. Spray,Janette F. Strasburger,Wayne Tworetzky,Jack Rychik +18 more
TL;DR: This statement highlights what is currently known and recommended on the basis of evidence and experience in the rapidly advancing and highly specialized field of fetal cardiac care.
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Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care.
TL;DR: The benefits of increasing body coverage are discussed, the efforts to develop a first-generation total- body PET/CT scanner are described, selected application areas for total-body PET are reviewed, and the impact of further improvements in time-of-flight PET is project.
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A dynamic 4D probabilistic atlas of the developing brain
Maria Kuklisova-Murgasova,Paul Aljabar,Latha Srinivasan,Serena J. Counsell,Valentina Doria,Ahmed Serag,Ioannis S. Gousias,James P. Boardman,Mary A. Rutherford,A. David Edwards,Joseph V. Hajnal,Daniel Rueckert +11 more
TL;DR: In this article, the authors describe a 4D probabilistic atlas that allows dynamic generation of prior tissue probability maps for any chosen stage of neonatal brain development between 29 and 44 gestational weeks.
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A spatiotemporal atlas of MR intensity, tissue probability and shape of the fetal brain with application to segmentation
Piotr A. Habas,Kio Kim,James Corbett-Detig,François Rousseau,Orit A. Glenn,A. James Barkovich,Colin Studholme +6 more
TL;DR: Experimental results indicate that quadratic temporal models can correctly capture growth-related changes in the fetal brain anatomy and provide improvement in accuracy of atlas-based tissue segmentation.
Journal ArticleDOI
Fetal MRI: An approach to practice: A review
TL;DR: A practical approach to fetal MR imaging is provided, which shows the normal anatomy of the developing fetus is shown to contrast with a wide spectrum of fetal disorders.
References
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Journal ArticleDOI
Improvement in hindbrain herniation demonstrated by serial fetal magnetic resonance imaging following fetal surgery for myelomeningocele.
Leslie N. Sutton,N S Adzick,Larissa T. Bilaniuk,Mark P. Johnson,Timothy M. Crombleholme,Alan W. Flake +5 more
TL;DR: In this series of patients, fetal myelomeningocele closure resulted in improvement in hindbrain herniation as demonstrated by serial MRI scans.
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Exclusion of fetal ventriculomegaly with a single measurement: the width of the lateral ventricular atrium.
TL;DR: The ventricular atria in 100 healthy fetuses with gestational ages ranging from 14 to 38 menstrual weeks were evaluated and compared with those of 38 fetuses in whom ventriculomegaly had been diagnosed in utero, finding that the normal atrial diameter remained relatively constant throughout the gestational age range observed.
Journal Article
Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis, part 1.
Orit A. Glenn,A. J. Barkovich +1 more
TL;DR: This 2-part review summarizes some of the latest developments in MR imaging of the fetal brain and spine and its application to prenatal diagnosis and focuses on additional clinical applications of fetal MR imaging, including suspected abnormalities of the corpus callosum, malformations of cortical development, and spine abnormalities.
Journal ArticleDOI
Central Nervous System Anomalies Associated with Meningomyelocele, Hydrocephalus, and the Arnold-Chiari Malformation: Reappraisal of Theories Regarding the Pathogenesis of Posterior Neural Tube Closure Defects
TL;DR: The frequency and pattern of brain malformations associated with neural tube defects of some children with meningomyelocele suggest that such mal Formations may seriously affect intellectual outcome.
Journal ArticleDOI
Registration-based approach for reconstruction of high-resolution in utero fetal MR brain images.
François Rousseau,Orit A. Glenn,Bistra Iordanova,Claudia E. Rodríguez-Carranza,Daniel B. Vigneron,James Barkovich,Colin Studholme +6 more
TL;DR: Results indicate that this method promises a unique route to acquiring high-resolution MRI of the fetal brain in vivo allowing comparable quality to that of neonatal MRI.
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