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A. David Edwards
Researcher at King's College London
Publications - 260
Citations - 20127
A. David Edwards is an academic researcher from King's College London. The author has contributed to research in topics: Diffusion MRI & White matter. The author has an hindex of 68, co-authored 230 publications receiving 17494 citations. Previous affiliations of A. David Edwards include Imperial College London & Boston Children's Hospital.
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Journal ArticleDOI
Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial
Peter D. Gluckman,John S. Wyatt,Denis Azzopardi,Roberta A. Ballard,A. David Edwards,Donna M. Ferriero,Richard A. Polin,Charlene M.T. Robertson,Marianne Thoresen,Andrew Whitelaw,Alistair J. Gunn +10 more
TL;DR: Induced head cooling is not protective in a mixed population of infants with neonatal encephalopathy, but it could safely improve survival without severe neurodevelopmental disability in infants with less severe aEEG changes.
Journal ArticleDOI
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.
Wan-Fai Ng,Phillip J. Duggan,Frederique Ponchel,Giuseppe Matarese,Giovanna Lombardi,A. David Edwards,John D. Isaacs,Robert I. Lechler +7 more
TL;DR: The results suggest that CD4(+)CD25(+) cells represent a population of regulatory T cells that arise during fetal life and may play a key role in the prevention of autoimmune diseases in humans.
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Effects of Hypothermia for Perinatal Asphyxia on Childhood Outcomes
Denis Azzopardi,Brenda Strohm,Neil Marlow,Peter Brocklehurst,Aniko Deierl,Oya Eddama,Julia Goodwin,Henry L. Halliday,Edmund Juszczak,Olga Kapellou,Malcolm I. Levene,Louise Linsell,Omar Omar,Marianne Thoresen,Nora Tusor,Andrew Whitelaw,A. David Edwards +16 more
TL;DR: Moderate hypothermia after perinatal asphyxia resulted in improved neurocognitive outcomes in middle childhood.
Journal ArticleDOI
Emergence of resting state networks in the preterm human brain
Valentina Doria,Christian F. Beckmann,Tomoki Arichi,Nazakat Merchant,Michela Groppo,Federico Turkheimer,Serena J. Counsell,Maria Murgasova,Paul Aljabar,Rita G. Nunes,David J. Larkman,Geraint Rees,A. David Edwards +12 more
TL;DR: The results place the emergence of RSNs largely during the period of rapid neural growth in the third trimester of gestation, suggesting that they are formed before the acquisition of cognitive competencies in later childhood.
Journal ArticleDOI
Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic-ischaemic encephalopathy: a nested substudy of a randomised controlled trial
Mary A. Rutherford,Luca A. Ramenghi,A. David Edwards,Peter Brocklehurst,Henry L. Halliday,Malcolm I. Levene,Brenda Strohm,Marianne Thoresen,Andrew Whitelaw,Denis Azzopardi +9 more
TL;DR: In this article, the authors assessed cerebral lesions on MRI scans of infants who participated in the Total Body Hypothermia for Neonatal Encephalopathy (TOBY) trial.