Neurological Manifestations of IgG4-Related Disease.
TLDR
IgG4-RD typically responds well to treatment with glucocorticoids, although relapse is relatively common and treatment with a steroid-sparing agent or rituximab may be required.Citations
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IgG4-related intracranial disease
Shahine Goulam-Houssein,Jeffrey L Grenville,Katerina Mastrocostas,David G. Munoz,Amy Lin,Aditya Bharatha,Paraskevi A. Vlachou +6 more
TL;DR: The delayed diagnoses in the cases illustrates the diagnostic challenge that clinicians face in differentiating intracranial IgG4-RD from other infiltrative diseases such as sarcoidosis, granulomatous disease, tuberculosis and lymphoma.
Journal ArticleDOI
Clinical features of hypertrophic pachymeningitis in a center survey.
Gonçalo Cação,Margarida Calejo,José Eduardo Alves,Pedro Bettencourt Medeiros,Nuno Vila-Chã,Teresa Mendonça,Ricardo Taipa,Ana Martins da Silva,Joana Damásio +8 more
TL;DR: Although headache was the most common symptom, clinical presentation was varied, emphasizing the role of MRI in HP diagnosis, and the underlying etiologies were diverse, with only a few cases remaining idiopathic.
Journal ArticleDOI
Cavernous sinus lesions.
Kamran Munawar,Gopi Nayak,Girish M. Fatterpekar,Chandra N. Sen,David Zagzag,Elcin Zan,Mari Hagiwara +6 more
TL;DR: In this paper, the authors review the clinical and imaging findings of a number of pathologies involving the cavernous sinus, focusing on key features that can narrow the differential diagnosis and, in some cases, support a particular diagnosis.
Journal ArticleDOI
Immunoglobulin G4–related disease mimicking an epidural spinal cord tumor: case report
TL;DR: A case of immunoglobulin G4-related disease (IgG4-RD) presenting as a paraspinal, epidural mass is reported, with results of fine-needle aspiration and CT-guided biopsy inconclusive.
Journal ArticleDOI
Nerve biopsy: Current indications and decision tools.
Dev Nathani,Dev Nathani,Judith M. Spies,Judith M. Spies,Michael Barnett,Michael Barnett,John D. Pollard,John D. Pollard,Min-Xia Wang,Min-Xia Wang,Claudia Sommer,Matthew C. Kiernan,Matthew C. Kiernan +12 more
TL;DR: A review of the current indications for nerve biopsies and some of the issues surrounding its use is presented in this article, where alternative diagnostic modalities that may help to supplant or reduce the use of nerve biopsy as a diagnostic test are discussed.
References
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High serum IgG4 concentrations in patients with sclerosing pancreatitis.
Hideaki Hamano,Shigeyuki Kawa,Akira Horiuchi,Hiroshi Unno,Naoyuki Furuya,Taiji Akamatsu,Mana Fukushima,Toshio Nikaido,Kohzo Nakayama,Nobuteru Usuda,Kendo Kiyosawa +10 more
TL;DR: Patients with sclerosing pancreatitis have high serum IgG4 concentrations, providing a useful means of distinguishing this disorder from other diseases of the pancreas or biliary tract.
Journal ArticleDOI
Consensus statement on the pathology of IgG4-related disease
Vikram Deshpande,Yoh Zen,John Kc Chan,Eunhee E Yi,Yasuharu Sato,Tadashi Yoshino,Günter Klöppel,J. Godfrey Heathcote,Arezou Khosroshahi,Judith A. Ferry,Rob C. Aalberse,Daniel Bloch,William R. Brugge,Adrian C Bateman,Mollie N. Carruthers,Suresh T. Chari,Wah Cheuk,Lynn D. Cornell,Carlos Fernandez-del Castillo,David G. Forcione,Daniel L. Hamilos,Terumi Kamisawa,Satomi Kasashima,Shigeyuki Kawa,Mitsuhiro Kawano,Gregory Y. Lauwers,Yasufumi Masaki,Yasuni Nakanuma,Kenji Notohara,Kazuichi Okazaki,Ji Kon Ryu,Takako Saeki,Dushyant V. Sahani,Thomas C. Smyrk,James Robert Stone,Masayuki Takahira,George Webster,Motohisa Yamamoto,Giuseppe Zamboni,Hisanori Umehara,John H. Stone +40 more
TL;DR: This statement proposes a terminology scheme for the diagnosis of IgG4-related disease that is based primarily on the morphological appearance on biopsy, and advocates the use of strict criteria for accepting newly proposed entities or sites as components of the IgG 4- related disease spectrum.
Journal ArticleDOI
Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011
Hisanori Umehara,Kazuichi Okazaki,Yasufumi Masaki,Mitsuhiro Kawano,Motohisa Yamamoto,Takako Saeki,Shoko Matsui,Tadashi Yoshino,Shigeo Nakamura,Shigeyuki Kawa,Hideaki Hamano,Terumi Kamisawa,Toru Shimosegawa,Akira Shimatsu,Seiji Nakamura,Tetsuhide Ito,Kenji Notohara,Takayuki Sumida,Yoshiya Tanaka,Tsuneyo Mimori,Tsutomu Chiba,Michiaki Mishima,Toshifumi Hibi,Hirohito Tsubouchi,Kazuo Inui,Hirotaka Ohara +25 more
TL;DR: The comprehensive diagnostic criteria for IgG4-RD are practically useful for general physicians and nonspecialists and have increased the sensitivity of diagnosis to 100% for Igg4-related MD, KD, and AIP.
Journal ArticleDOI
Chronic pancreatitis caused by an autoimmune abnormality : proposal of the concept of autoimmune pancreatitis
Kenji Yoshida,Fumitake Toki,Tadashi Takeuchi,Shin-ichiro Watanabe,Keiko Shiratori,Naoaki Hayashi +5 more
TL;DR: In this paper, the authors reported a case of chronic pancreatitis in which an autoimmune mechanism is involved in the etiology and summarized the cases of pancreatitis suspected of being caused by an auto-antibody-positive mechanism in the Japanese and English literature.
Related Papers (5)
IgG4-related hypertrophic pachymeningitis: clinical features, diagnostic criteria, and treatment.
Consensus statement on the pathology of IgG4-related disease
Vikram Deshpande,Yoh Zen,John Kc Chan,Eunhee E Yi,Yasuharu Sato,Tadashi Yoshino,Günter Klöppel,J. Godfrey Heathcote,Arezou Khosroshahi,Judith A. Ferry,Rob C. Aalberse,Daniel Bloch,William R. Brugge,Adrian C Bateman,Mollie N. Carruthers,Suresh T. Chari,Wah Cheuk,Lynn D. Cornell,Carlos Fernandez-del Castillo,David G. Forcione,Daniel L. Hamilos,Terumi Kamisawa,Satomi Kasashima,Shigeyuki Kawa,Mitsuhiro Kawano,Gregory Y. Lauwers,Yasufumi Masaki,Yasuni Nakanuma,Kenji Notohara,Kazuichi Okazaki,Ji Kon Ryu,Takako Saeki,Dushyant V. Sahani,Thomas C. Smyrk,James Robert Stone,Masayuki Takahira,George Webster,Motohisa Yamamoto,Giuseppe Zamboni,Hisanori Umehara,John H. Stone +40 more
Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011
Hisanori Umehara,Kazuichi Okazaki,Yasufumi Masaki,Mitsuhiro Kawano,Motohisa Yamamoto,Takako Saeki,Shoko Matsui,Tadashi Yoshino,Shigeo Nakamura,Shigeyuki Kawa,Hideaki Hamano,Terumi Kamisawa,Toru Shimosegawa,Akira Shimatsu,Seiji Nakamura,Tetsuhide Ito,Kenji Notohara,Takayuki Sumida,Yoshiya Tanaka,Tsuneyo Mimori,Tsutomu Chiba,Michiaki Mishima,Toshifumi Hibi,Hirohito Tsubouchi,Kazuo Inui,Hirotaka Ohara +25 more