Journal ArticleDOI
Nickel-Catalyzed Decarbonylative Addition of Anhydrides to Alkynes
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TLDR
An intermolecular nickel-catalyzed addition reaction has been developed where phthalic anhydrides react with alkynes to afford substituted isocoumarins, implying reductive elimination of Ni(0) promoted by ZnCl(2) cocatalyst as the key step of the catalytic cycle.Abstract:
An intermolecular nickel-catalyzed addition reaction has been developed where phthalic anhydrides react with alkynes to afford substituted isocoumarins. A mechanistic rationale is proposed, implying reductive elimination of Ni(0) promoted by ZnCl2 cocatalyst as the key step of the catalytic cycle.read more
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Journal ArticleDOI
Cross-coupling of aromatic esters and amides
TL;DR: In this review, recent advances in metal-catalyzed cross-coupling reactions of aromatic esters and amides are discussed.
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Alkenylation of Arenes and Heteroarenes with Alkynes.
TL;DR: This review is focused on the analysis of current data on new methods of alkenylation of arenes and heteroarenes with alkynes by transition metal catalyzed reactions, Bronsted/Lewis acid promoted transformations, and others.
Journal ArticleDOI
Nickel-Catalyzed Decarbonylative Borylation of Amides: Evidence for Acyl C−N Bond Activation
TL;DR: A nickel/N-heterocyclic carbene catalytic system has been established for decarbonylative borylation of amides with B2 nep2 by C-N bond activation and the structure of an acyl nickel complex was confirmed by X-ray analysis.
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Direct Acylation of C(sp(3))-H Bonds Enabled by Nickel and Photoredox Catalysis.
Candice L. Joe,Abigail G. Doyle +1 more
TL;DR: Using nickel and photoredox catalysis, the direct functionalization of C(sp(3))-H bonds of N-aryl amines by acyl electrophiles is described, which affords a diverse range of α-amino ketones at room temperature and is amenable to late-stage coupling of complex and biologically relevant groups.
Journal ArticleDOI
Rh-Catalyzed decarbonylative coupling with alkynes via C-C activation of isatins.
Rong Zeng,Guangbin Dong +1 more
TL;DR: A [5 + 2 - 1] transformation though catalytic decarbonylative coupling between isatins and alkynes, which provides a unique way to synthesize 2-quinolinone derivatives, which can be coupled efficiently with high regioselectivity.