Journal ArticleDOI
Obesity, metabolism, and the sympathetic nervous system.
Lewis Landsberg,Diane R. Krieger +1 more
TLDR
Insulin-mediated glucose metabolism within central neurons associated with the ventromedial hypothalamus (VMH) plays an important role in the relationship between dietary intake and SNS activity as indicated by the following observations.About:
This article is published in American Journal of Hypertension.The article was published on 1989-03-01. It has received 215 citations till now. The article focuses on the topics: Sympathetic nervous system & Norepinephrine.read more
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Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease
TL;DR: In summary, insulin resistance appears to be a syndrome that is associated with a clustering of metabolic disorders, including non-insulin-dependent diabetes mellitus, obesity, hypertension, lipid abnormalities, and atherosclerotic cardiovascular disease.
Journal ArticleDOI
Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans
TL;DR: This study suggests that acute increases in plasma insulin within the physiological range elevate sympathetic neural outflow but produce forearm vasodilation and do not elevate arterial pressure in normal humans.
Journal ArticleDOI
The Medical Risks of Obesity
TL;DR: Evidence for significant associations of obesity with comorbidities is reviewed to provide information useful for optimal patient management to allow health care professionals to identify and implement appropriate interventions to reduce patient risk and mortality.
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Health implications of obesity.
TL;DR: Obesity is more dangerous than gluteal-femoral obesity because the amount of intraabdominal fat seems to determine much of the increased peril; therefore, risks of cardiovascular disease, stroke, hypertension, and diabetes increase with abdominal obesity, even independently of total fat mass.
Journal ArticleDOI
The Kidney, Hypertension, and Obesity
TL;DR: There are many unanswered questions about the mechanisms of obesity hypertension and renal disease, but this is one of the most promising areas for future research, especially in view of the growing, worldwide "epidemic" of obesity.