On the pathogenesis of syringomyelia: a review.
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TLDR
Cord ischaemia, venous congestion and transport of fluid along perivascular spaces may all play a part in the maintainance of cord cavities or the progression of the clinical disabilities.Abstract:
Discussion of the pathogenesis of syringomyelia involves considering the origin of the fluid and also the forces which cause that fluid to break down the structure of the cord. When cerebrospinal f...read more
Citations
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Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients.
Thomas H. Milhorat,Mike W. Chou,Mike W. Chou,Elizabeth M. Trinidad,Elizabeth M. Trinidad,Roger W. Kula,Roger W. Kula,Menachem Mandell,Chantelle M. Wolpert,Marcy C. Speer +9 more
TL;DR: These data support accumulating evidence that CMI is a disorder of the para-axial mesoderm that is characterized by underdevelopment of the posterior cranial fossa and overcrowding of the normally developed hindbrain.
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Asymptomatic Chiari Type I malformations identified on magnetic resonance imaging
TL;DR: It is suggested that the isolated finding of tonsillar herniation is of limited prognostic utility and must be considered in the context of all available clinical and radiographic data.
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Symptomatic Chiari malformations. An analysis of presentation, management, and long-term outcome.
TL;DR: A model based on the presence or absence of atrophy, ataxia, and scoliosis at the time of the preoperative examination has been generated that allows prediction of long-term outcome at the 95% confidence level.
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Transoral-transpharyngeal approach to the anterior craniocervical junction: Ten-year experience with 72 patients
TL;DR: The anterior transoral-transpharyngeal operation to correct ventral irreducible compression of the cervicomedullary junction was utilized in 72 individuals, and there were two deaths within 30 days of surgery.
Journal ArticleDOI
Pathological basis of spinal cord cavitation in syringomyelia: analysis of 105 autopsy cases.
TL;DR: It is concluded that syringomyelia has several distinct cavitary patterns with different mechanisms of pathogenesis that probably determine the clinical features of the condition.
References
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Journal ArticleDOI
The distending force in the production of communicating syringomyelia
TL;DR: It is suggested that partial blockage of the subarachnoid space in the region of the cisterna magna is responsible for cerebrospinal fluid being directed into the communication, thereby providing an intermittent distending force which may be active for many years.
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Cerebrospinal fluid pressure changes in response to coughing.
TL;DR: It is suggested that Froin's syndrome, central subarachnoid pouches and syringobulbia may be associated with upward pressure waves and the merits and limitations of cough impulse as a clinical test for spinal blockage are discussed.
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Difficult labour as a cause of communicating syringomyelia
TL;DR: The results of a questionnaire suggest a high incidence of difficult labour in the mothers of syringomyelia patients, and it seems likely that birth trauma may be a cause of tonsillar descent through the foramen magnum and of arachnoiditis; both conditions are often present.
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Experimental communicating syringomyelia in dogs after cisternal kaolin injection. Part 1. Morphology.
Bernard Williams,James Bentley +1 more
TL;DR: The dogs all had arachnoiditis, all had hydrocephalus and all had a radiologically demonstrable communication of the cavities with the 4th ventricle, findings which are unusual in human syringomyelia.