Journal ArticleDOI
Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective long-chain omega-3 fatty acids as the metastatic antagonists.
Arwa Morshed,Salauddin Al Azad,Md. Abdur Rashid Mia,M. F. Uddin,T. Ema,Rukaiya Binte Yeasin,Sanjida Ahmed Srishti,Pallab K. Sarker,Rubaita Younus Aurthi,Farhan Jamil,Nure Sharaf Nower Samia,Partha Biswas,Iffat-Ara Sharmeen,Rasel Ahmed,Mahbuba Siddiquy,Nurunnahar +15 more
About:
This article is published in Molecular Diversity.The article was published on 2022-11-29. It has received 6 citations till now. The article focuses on the topics: Medicine & Lapatinib.read more
Citations
More filters
Journal ArticleDOI
Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development Approach
Partha Biswas,Shabana Bibi,Qudsia Yousafi,Asim Mehmood,Shahzad Saleem,Awais Ihsan,Dipta Dey,Nazmul Hasan Zilani,Md. Nazmul Hasan,R. M. Saleem,Aeshah Ali Awaji,Usama A. Fahmy,Mohamed M. Abdel-Daim +12 more
TL;DR: In this article , an evaluation of the expression and predictive significance of the MDM2 gene in brain lower grade glioma (LGG) cancer was carried out using onco-informatics pipelines.
Journal ArticleDOI
Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings of the CD81 receptor: a combined in silico and in vivo study
Anika Jabin,M. F. Uddin,Salauddin Al Azad,Ashfaque Rahman,Fawzia Tabassum,Pritthy Sarker,Arwa Morshed,Samiur Rahman,Fatima Fairuz Raisa,Musfiqur Rahman Sakib,A. H. Olive,Tabassum Islam,Shahlaa Zernaz Ahmed,Partha Biswas,Mst. Umme Habiba,Mahbuba Siddiquy +15 more
TL;DR: In this paper , the target-specificity and therapeutic potentiality of α, β, and δ subunits of amyrin, as novel bioactive components against the HCV influx mechanism were investigated.
Journal ArticleDOI
Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus
Asif Abdullah,Partha Biswas,Mohd Shaun Farleen Sahabuddin,Afiya Mubasharah,Dhrubo Ahmed Khan,Akram Hossain,Tanima Roy,Nishat Md. R. Rafi,Dipta Dey,Md. Nazmul Hasan,Shabana Bibi,Mahmoud Moustafa,Ali A. Shati,Hesham Hassan,Ruchika Garg +14 more
TL;DR: In this article , the in-silico analysis revealed that 7-Deacetyl-7-oxogedunin had the highest negative docking score of −8.9 Kcal/mol and also demonstrated standard stability in a 100-ns molecular dynamic simulation performed with insulin receptor ectodomain.
Journal ArticleDOI
Phyllanthus emblica (Amla) methanolic extract regulates multiple checkpoints in 15-lipoxygenase mediated inflammopathies: Computational simulation and in vitro evidence
Md. Arman Sharif,Arman Mahmud Khan,Rahagir Salekeen,Md. Hafijur Rahman,Sakib Mahmud,Shabana Bibi,Partha Biswas,M. Nazmul Hasan,Kazi Islam,S. M. Mahbubur Rahman,Md. Emdadul Islam,Abdulrahman Alshammari,Metab Alharbi,Abdul Hayee +13 more
TL;DR: Amla (Phyllanthus emblica) has been used in traditional folk medicine to prevent and cure a variety of inflammatory diseases as discussed by the authors , which has been shown to have significant antioxidant, anti-inflammatory, and anticoagulation activity.
Journal ArticleDOI
Wireless Power System for Video Capsule Endoscopes: Design, Development, Implementation, and Analysis
TL;DR: In this article , the authors used a wireless means to power the Video Capsule Endoscope (VCE) using inductive magnetic coupling, in which the transmitting circuit generates a magnetic field and the receiving circuit, located inside the VCE, receives AC power by electromagnetic induction.
References
More filters
Journal ArticleDOI
SwissADME: A free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
TL;DR: The new SwissADME web tool is presented that gives free access to a pool of fast yet robust predictive models for physicochemical properties, pharmacokinetics, drug-likeness and medicinal chemistry friendliness, among which in-house proficient methods such as the BOILED-Egg, iLOGP and Bioavailability Radar are presented.
Journal ArticleDOI
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function.
David Warde-Farley,Sylva L. Donaldson,Ovi Comes,Khalid Zuberi,Rashad Badrawi,Pauline Chao,Max Franz,Chris Grouios,Farzana Kazi,Christian Lopes,Anson Maitland,Sara Mostafavi,Jason Montojo,Quentin Shao,George Wright,Gary D. Bader,Quaid Morris +16 more
TL;DR: The high accuracy of the GeneMANIA prediction algorithm, an intuitive user interface and large database make Gene MANIA a useful tool for any biologist.
Journal ArticleDOI
CASTp: Computed Atlas of Surface Topography of proteins
TL;DR: Computed Atlas of Surface Topography of proteins (CASTp) provides an online resource for locating, delineating and measuring concave surface regions on three-dimensional structures of proteins, including pockets located on protein surfaces and voids buried in the interior of proteins.
Journal ArticleDOI
Understanding survival analysis: Kaplan-Meier estimate.
TL;DR: The Kaplan-Meier estimate is one of the best options to be used to measure the fraction of subjects living for a certain amount of time after treatment and can be used in Ayurveda research when they are comparing two drugs and looking for survival of subjects.
Journal ArticleDOI
Accurate prediction of the relative potencies of members of a series of kinase inhibitors using molecular docking and MM-GBSA scoring.
TL;DR: The ability of molecular docking, using the program Glide and an MM-GBSA postdocking scoring protocol, to correctly rank a number of congeneric kinase inhibitors was assessed and suggests that this may be useful for the design of inhibitors in the lead optimization phase of drug discovery.