Journal ArticleDOI
Parachlorophenylalanine and habituation to repetitive auditory startle stimuli in rats
TLDR
Results suggest that brain serotonin plays a role in inhibitory processes and that treated rats exhibit heightened reactivity to startle stimuli following exposure to novel stimuli.About:
This article is published in Physiology & Behavior.The article was published on 1970-11-01. It has received 136 citations till now. The article focuses on the topics: Startle response & Habituation.read more
Citations
More filters
Journal ArticleDOI
A perceptual-defensive-recuperative model of fear and pain
TL;DR: A model of fear and pain is presented in which the two are assumed to activate totally different classes of behavior, and it is assumed that fear triggers the endorphin mechanism, thereby inhibiting pain motivation and recuperative behaviors that might compete with effective defensive behavior.
Journal ArticleDOI
Sensation seeking: A comparative approach to a human trait
TL;DR: A model is suggested that relates mood, behavioral activity, sociability, and clinical states to activity of the central catecholamine neurotransmitters and to neuroregulators and other transmitters that act in opposite ways on behavior or stabilize activity in the arousal systems.
Book ChapterDOI
The Mammalian Startle Response
TL;DR: It would be useful to study a relatively simple behavior that can be elicited in mammals and that is sensitive to a variety of experimental treatments to approach the problem at this level.
Journal ArticleDOI
Startle response models of sensorimotor gating and habituation deficits in schizophrenia.
TL;DR: Evidence is presented supporting the involvement of mesolimbic dopaminergic systems in the modulation of prepulse inhibition or sensorimotor gating and the importance of central serotonergic systemsIn the habituation of startle.
References
More filters
Journal Article
p-CHLOROPHENYLALANINE: A SPECIFIC DEPLETOR OF BRAIN SEROTONIN
B K Koe,A Weissman +1 more
TL;DR: The results suggest that p -chlorophenylalanine may effect 5HT depletion by inhibiting the biosynthesis of this monoamine, possibly by blocking tryptophan hydroxylation.
Journal ArticleDOI
Suppression of auditory nerve activity by stimulation of efferent fibers to cochlea.
TL;DR: This observation means that nerve impulses aroused in the medulla by the electrical stimulation pass out to the cochlea where, through a physiological interaction, they suppress the expected auditory nerve inflow.
Journal ArticleDOI
Reflexive fighting in response to aversive stimulation.
Roger E. Ulrich,N. H. Azrin +1 more
TL;DR: Reflexive fighting was elicited between paired rats as a reflex reaction to electric shock prior to any specific conditioning, and under optimal conditions fighting was consistently elicited by shock regardless of the rat's sex, strain, previous familiarity with each other, or the number present during shock.
Journal ArticleDOI
Modification of electric activity in cochlear nucleus during attention in unanesthetized cats.
Journal ArticleDOI
The effects of p-chlorophenylalanine, a serotonin depletor, on avoidance acquisition, pain sensitivity and related behavior in the rat
TL;DR: The data suggest that the alteration in pain sensitivity was a result of serotonin depletion in the central nervous system, and the compound resulted in decreased “emotional reactivity” (as measured by a conditioned emotional stimulus) and some decreased spontaneous motor activity.