Journal ArticleDOI
Plasticity of connections of the olfactory sensory neuron: Regeneration into the forebrain following bulbectomy in the neonatal mouse
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It is demonstrated that following bulbectomy and retrograde degeneration of olfactory neurons, the cells can regenerate in the absence of their normal target, and the newly formed axons can penetrate a ‘foreign’ environment, the cerebral cortex, and form typical glomerular structures and corresponding sensory synapses.About:
This article is published in Neuroscience.The article was published on 1979-06-01. It has received 170 citations till now. The article focuses on the topics: Olfactory system & Olfactory ensheathing glia.read more
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Journal ArticleDOI
Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus
Jack M. Parent,Timothy W. Yu,Rebecca T. Leibowitz,Daniel H. Geschwind,Robert S. Sloviter,Daniel H. Lowenstein +5 more
TL;DR: Observations indicate that prolonged seizure discharges stimulate dentate granule cell neurogenesis, and that hippocampal network plasticity associated with epileptogenesis may arise from aberrant connections formed by newly born dentategranule cells.
Journal ArticleDOI
Isolation, Characterization, and use of Stem Cells from the CNS
TL;DR: Because in vitro culture conditions are unlikely to provide all of the factors necessary for inducing the proliferation and differentiation of neural precursors, recent studies have explored the properties of well-characterized precursor populations after implantation back into specific regions of the developing or adult CNS.
Journal ArticleDOI
Esthesioneuroblastoma: a meta-analysis and review
TL;DR: The histopathological grading according to Hyams and the presence of cervical lymph-node metastases emerged as prognostic factors and a combination of surgery and radiotherapy seems to be the optimum approach to treatment.
Journal ArticleDOI
Vertebrate Olfactory Reception
TL;DR: Olfactory recognition is mediated by a large ensemble' of sensory cells, each conveying a fraction of the information that signifies the nature of the odorant and its concentration, which corresponds to the combined Stereo chemical/Functional-group theories of olfaction.
Book
An Odor is Not Worth a Thousand Words: From Multidimensional Odors to Unidimensional Odor Objects
Yaara Yeshurun,Noam Sobel +1 more
TL;DR: It is argued that the boundaries of an odor object are determined by its pleasantness, which--unlike something material and more like an emotion--remains poorly delineated with words.
References
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Journal ArticleDOI
The unlabeled antibody enzyme method of immunohistochemistry preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes:
TL;DR: PAP was heterogeneous on electrophoresis, homogeneous on sedimentation, diffusion and electron microscopy and consisted of pentagons with diameters of 205 Å, with the unexpected ratio of PO to anti-PO presumed to be due to stabilization by the pentagonal shape.
Journal ArticleDOI
Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs
Michael S. Kaplan,James W. Hinds +1 more
TL;DR: Three-month-old rats were injected intraperitoneally with [3H]thymidine and labeled cells in the granular layers of dentate gyrus and olfactory bulb were confirmed as neurons by electron microscopy of reembedded 1-micrometer sections.
Journal ArticleDOI
Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neurons
TL;DR: The morphological stages of maturation and ageing of this exceptional neuron have been described both at light and electron microscopical levels and the neural elements have been classified as: basal cells proper, globose basal cells, and neurons.
Journal ArticleDOI
Neurogenesis and neuron regeneration in the olfactory system of mammals. II. Degeneration and reconstitution of the olfactory sensory neurons after axotomy.
TL;DR: The retrograde degeneration affecting olfactory sensory neurons of rats after severance of their axons is described and the reconstitution of new neurons originating from stem cells located at the base of the Olfactory neuroepithelium is illustrated.
Book ChapterDOI
Continuous Nerve Cell Renewal in the Olfactory System
TL;DR: The olfactory system has been long reported as one of the most phylogenetically primitive (Ariens Kappers et al., 1967), because of the peripheral location of its neurons and the relatively conspicuous development in lower vertebrates.