Journal ArticleDOI
Polyps and carcinoma of the large bowel in the South African Bantu.
TLDR
The South African Bantu has an unusual pattern of disease of the large bowel but for all practical purposes he does not have Crohn's diseaseulcerative colitisor diverticulosis and therefore should be concerned with prevention as well as detection of large bowel cancer.Abstract:
The South African Bantu has an unusual pattern of disease of the large bowel. for all practical purposes he does not have Crohn's diseaseulcerative colitisor diverticulosis. Cancer of the large bowel is of extremely low frequencyand this series of 96 cases was never associated with adenomatous polyps. in 14,000 autopsiesno adenomatous polyps were found. During a 12‐year period at the Baragwanath Hospital (2,000 beds)only 6 adenomatous polyps were submitted to Surgical Pathology. Low incidence of carcinoma of the large bowel is undoubtedly environmental rather than genetic. in direct contrast to the United Statesthe Bantu has an extremely bulky diet and increased frequency of defecation. Bacterial flora may also be important. Because of these factorswe should be concerned with prevention as well as detection of large bowel cancer.read more
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Journal ArticleDOI
The evolution of cancer of the colon and rectum.
TL;DR: Evidence is presented which suggests that most cancers of the colon and rectum have evolved through the polyp‐cancer sequence although the majority of adenomas do not become cancerous during a normal adult life span.
Journal ArticleDOI
Epidemiology of cancer of the colon and rectum
TL;DR: It seems likely that carcinogens produced by the action of an abnormal bacterial flora when held for a prolonged period in a concentrated form in contact with the bowel mucosa may account for the high incidence of these diseases in economically developed countries.
Book
Diverticular Disease of the Colon
Neil Stollman,Jeffrey B. Raskin +1 more
TL;DR: The incidence, pathophysiology, clinical presentation, and management of diverticular disease of the colon and its complications are reviewed.
Journal ArticleDOI
Aetiology of adenoma--carcinoma sequence in large bowel.
TL;DR: A hypothesis, based on epidemiological and histopathological data, is proposed to account for the aetiology of colorectal adenomas and carcinomas.
Journal ArticleDOI
Diverticular disease of the colon, a 20th century problem.
Neil S. Painter,D.P. Burkitt +1 more
References
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Book
Surgery of the Anus, Rectum and Colon
TL;DR: Colorectal Cancer: Epidemiology, Aetiology, Pathology, Clinical Features and, Diagnosis Screening, N S Williams.
Journal ArticleDOI
Cancer Of The Colon: The Influence Of The No-touch Isolation Technic On Survival Rates
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