Journal ArticleDOI
Porous ceramics as bone graft substitutes in long bone defects: a biomechanical, histological, and radiographic analysis.
Kenneth D. Johnson,Kerek E. Frierson,Tony S. Keller,Charles Cook,Robert Scheinberg,Joseph E. Zerwekh,Laura Meyers,Marcus F. Sciadini +7 more
TLDR
Biomechanical testing and radiographic evauation revealed that the addition of bone marrow aspirate was essential for tricalcium phosphate and hydroxyapatite to achieve results comparable with those of cancellous bone, and this degradation took place only after a degree of mechanical competence necessary for weight‐bearing was achieved.About:
This article is published in Journal of Orthopaedic Research.The article was published on 1996-05-01. It has received 231 citations till now. The article focuses on the topics: Cancellous bone & Long bone.read more
Citations
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Journal ArticleDOI
Bone substitutes: an update.
TL;DR: An overview of bone grafts and graft substitutes available for clinical applications is presented and osteoinductive growth factors, osteogenic cells, and an osteoconductive scaffold are provided.
Journal ArticleDOI
The role of growth factors in the repair of bone. Biology and clinical applications.
TL;DR: The mechanisms of action, functions, and potential clinical applications of a variety of growth factors that may be used clinically to treat problems associated with the repair of bone are defined.
Journal ArticleDOI
The effect of implants loaded with autologous mesenchymal stem cells on the healing of canine segmental bone defects
TL;DR: Autologous cultured bone-marrow-derived mesenchymal stem cells that had been loaded onto porous ceramic cylinders elicited the healing of critical-sized segmental bone defects in dogs, suggesting that this approach may provide an alternative to autologous bone-grafting.
Journal ArticleDOI
Collagen-hydroxyapatite composites for hard tissue repair.
D. A. Wahl,Jan T. Czernuszka +1 more
TL;DR: The results outlined on mechanical properties, cell culturing and de-novo bone growth of these devices relate to the efficiency of these to be used as future bone implants, as well as improving the method of creating composite structures.
Journal ArticleDOI
Osteoconduction at porous hydroxyapatite with various pore configurations
TL;DR: The biomechanical test showed that the ultimate compressive strength increased significantly in the phi300 microm sized cylindrical-type, and in the sponge- and cross-types eight weeks after implantation.
References
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Journal ArticleDOI
Morbidity at bone graft donor sites.
TL;DR: A review of the medical records of 239 patients with 243 autogenous bone grafts was undertaken to document the morbidity at the donor sites, finding that there was a much higher complication rate if the incision used for the surgery was also the sameincision used to harvest the bone graft.
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Calcium phosphate ceramics as hard tissue prosthetics.
TL;DR: Calcium Phosphate Ceramics as Hard Tissue Prosthetics and its Applications in Orthopaedics and Related Research.
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Donor site pain from the ilium. A complication of lumbar spine fusion
BN Summers,Stephen M. Eisenstein +1 more
TL;DR: Chronic pain at the donor site was reported by 25% of 290 patients who had undergone anterior lumbar spine fusion for low back pain and patients with a clinically unsatisfactory result from the spine fusion also had a significantly higher prevalence of donor site pain.
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Donor-site morbidity after harvesting rib and iliac bone.
TL;DR: Morbidity following 104 bone graft harvesting operations in 72 patients is documented and early morbidity of iliac donor sites was found to be far greater than that of rib donor sites.
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Hydroxyapatite formed from Coral Skeletal Carbonate by Hydrothermal Exchange
TL;DR: Porous microstructures, having potential for prosthetic applications, consisting of hydroxapatite and of whitlockite are prepared by employing exchange reactions at elevated temperatures and pressures to achieve optimum mechanical and physical properties for a particular application.