Journal ArticleDOI
Prediction of nipple and areola involvement in breast cancer
TLDR
In the one-fifth of cases where the tumour is over 2.5 cm from the areola, preserving the nipple and areola for reconstruction may be worthwhile and some other predictive test for nipple involvement would be necessary.Abstract:
Aims. To find a pre-operative test for nipple and areola involvement in breast cancer.Methods. Areola-tumour distance was measured in 140 consecutive patients (median age 45, range: 23-83) undergoing a mastectomy. We analysed whether nipple and areola correlated with areola-tumour distance, tumour size, nodal status, perinodal involvement and lymphatic embolization.Results. The nipple was involved in 22 (16%) cases and this correlated with tumour size, number of lymph nodes, perinodal extension and presence of lymphatic emboli. In all these 22 cases, the tumour was within 2.5 cm of the areola. Tumour size, however, could not predict nipple involvement in tumours within 2.5 cm of the areolar edge.Conclusions. In the one-fifth of cases where the tumour is over 2.5 cm from the areola, preserving the nipple and areola for reconstruction may be worthwhile. In remaining cases, some other predictive test for nipple involvement would be necessary.read more
Citations
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Journal ArticleDOI
Skin-sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction is an oncologically safe procedure.
B. Gerber,Annette Krause,Toralf Reimer,Heiner Müller,Ingrid Küchenmeister,Joseph Makovitzky,Günther Kundt,Klaus Friese +7 more
TL;DR: In patients who are candidates for a mastectomy and tumors distant from the nipple, SSM with intraoperative frozen section of the NAC ground offers the opportunity of NAC conservation without increasing the risk of local recurrences.
Journal ArticleDOI
Nipple-sparing mastectomy for breast cancer and risk reduction: oncologic or technical problem?
Virgilio Sacchini,José Aristodemo Pinotti,Alfredo Carlos Simões Dornellas de Barros,Alberto Luini,Alfonso M. Pluchinotta,Marianne Pinotti,Marcelo Gennari Boratto,Marco D. Ricci,Carlos Alberto Ruiz,A.C.T. Nisida,Paolo Veronesi,Jean Yves Petit,Paolo Arnone,Fabio Bassi,Joseph J. Disa,Carlos A. Garcia-Etienne,Patrick I. Borgen +16 more
TL;DR: Nipple-sparing mastectomy in the risk-reducing and breast cancer-treatment settings may be feasible in selected patients and should be the subject of additional prospective clinical trials.
Journal ArticleDOI
Nipple-Sparing Mastectomy for Breast Cancer and Risk-Reducing Surgery: The Memorial Sloan-Kettering Cancer Center Experience
Paulo R. de Alcantara Filho,Deborah Capko,John Mitchel Barry,Monica Morrow,Andrea L. Pusic,Virgilio Sacchini +5 more
TL;DR: Although NSM is not standard, the experience supports the selective use of NSM in both prophylactic and malignant settings, as well as for therapeutic purposes.
Journal ArticleDOI
Nipple-sparing mastectomy: technique and results of 54 procedures.
Joseph P. Crowe,Julian A. Kim,Randall J. Yetman,Jillian E. Banbury,Rebecca J. Patrick,Deborah Baynes +5 more
TL;DR: Nipple-sparing mastectomy (NSM) combines a skin-spared mastectomy with preservation of the NAC, intraoperative pathological assessment of the nipple tissue core, and immediate reconstruction, thereby permitting better cosmesis for patients undergoing total mastectomy.
Journal ArticleDOI
Nipple sparing mastectomy with nipple areola intraoperative radiotherapy: one thousand and one cases of a five years experience at the European institute of oncology of Milan (EIO)
J.Y. Petit,Umberto Veronesi,Roberto Orecchia,Piercarlo Rey,Stefano Martella,Florence Didier,Giuseppe Viale,Paolo Veronesi,Alberto Luini,Viviana Galimberti,R. Bedolis,Mario Rietjens,Cristina Garusi,F. De Lorenzi,Riccardo Bosco,Andrea Manconi,Giovanni Ivaldi,O. Youssef +17 more
TL;DR: In a group of patients characterized by a very close free margin under the areola, no local recurrence was observed, and a novel radiosurgical treatment combining subcutaneous mastectomy with intraoperative radiotherapy (ELIOT) is proposed to reduce the risk of retro areolar recurrence.
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