C
C Davies
Researcher at University of Oxford
Publications - 42
Citations - 31890
C Davies is an academic researcher from University of Oxford. The author has contributed to research in topics: Breast cancer & Tamoxifen. The author has an hindex of 27, co-authored 40 publications receiving 29161 citations. Previous affiliations of C Davies include Clinical Trial Service Unit.
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Journal ArticleDOI
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
O. Abe,R. Abe,K. Enomoto,K. Kikuchi,H. Koyama,H. Masuda,Y. Nomura,K. Sakai,K. Sugimachi,T. Tominaga,J. Uchino,M. Yoshida,J. L. Haybittle,C Davies,V. J. Harvey,T. M. Holdaway,R. G. Kay,B. H. Mason,John F. Forbes,Nicholas Wilcken,M. Gnant,Raimund Jakesz,M. Ploner,H. M. A. Yosef,C. Focan,J. P. Lobelle,U. Peek,G. D. Oates,Janet T. Powell,M. Durand,L. Mauriac,A. Di Leo,Stella Dolci,M.J. Piccart,M. B. Masood,D. Parker,J. J. Price,Pierre Hupperets,Sue Jackson,Joseph Ragaz,Donna L. Berry,Gloria Broadwater,C. Cirrincione,Hyman B. Muss,Larry Norton,Raymond B. Weiss,H. Abu-Zahra,S. M. Portnoj,Michael J. Baum,Jack Cuzick,Joan Houghton,David Riley,N. H. Gordon,H. L. Davis,A. Beatrice,J. Mihura,A. Naja,Y. Lehingue,P. Romestaing,J. B. Dubois,Thierry Delozier,J. Mace-Lesec'h,P. Rambert,O. Andrysek,J. Barkmanova,Julie Owen,P. Meier,A Howell,G. C. Ribeiro,R. Swindell,R Alison,J Boreham,Matthew Clarke,Rory Collins,Sarah C. Darby,P. Elphinstone,Vaughan Evans,Jon Godwin,Richard Gray,C. S. Harwood,C. Hicks,Spencer L. James,Elizabeth MacKinnon,Paul McGale,Theresa McHugh,Graham M. Mead,Richard Peto,Yisong Wang,J. Albano,C. F. de Oliveira,H. Gervasio,J. Gordilho,H Johansen,Henning T. Mouridsen,Rebecca Gelman,J.R. Harris,I. C. Henderson,Charles L. Shapiro,K. W. Andersen,C. K. Axelsson,M. Blichert-Toft,S. Moller,Jens Overgaard,Marie Overgaard,Carsten Rose,B. Cartensen,T. Palshof,H. J. Trampisch,Otilia Dalesio,E.G.E. de Vries,Sjoerd Rodenhuis,H. van Tinteren,R. L. Comis,Nancy E. Davidson,Nicholas J. Robert,George W. Sledge,Douglass C. Tormey,William C. Wood,David Cameron,Udi Chetty,P. Forrest,W. Jack,J. Rossbach,Jan G. M. Klijn,A. D. Treurniet-Donker,W. L. J. van Putten,Alberto Costa,Umberto Veronesi,H. Bartelink,L. Duchateau,C. Legrand,RJ Sylvester,J.A. van der Hage,C.J.H. van de Velde,M. P. Cunningham,R. Catalano,R. H. Creech,Jacques Bonneterre,P. Fargeot,Pierre Fumoleau,Pierre Kerbrat,Moïse Namer,Walter Jonat,Manfred Kaufmann,Martin Schumacher,G. von Minckwitz,G. Bastert,H. Rauschecker,R. Sauer,Willi Sauerbrei,A.J. Schauer,A. de Schryver,L. Vakaet,M. Belfiglio,A. Nicolucci,F. Pellegrini,M. Sacco,M. Valentini,C. S. McArdle,D. C. Smith,E. Galligioni,Francesco Boccardo,AU Rubagotti,D. M. Dent,C. A. Gudgeon,A. Hacking,A. Erazo,J. Y. Medina,M. Izuo,Y. Morishita,H. Takei,I.S. Fentiman,John L. Hayward,R D Rubens,D. Skilton,H. Graeff,Fritz Jänicke,C. Meisner,H. R. Scheurlen,D. von Fournier,Urania Dafni,G. Fountzilas,P. Klefstrom,Carl Blomqvist,T. Saarto,R. Margreiter,Bernard Asselain,R. J. Salmon,J. R. Vilcoq,Rodrigo Arriagada,Christopher Hill,A. Laplanche,M. G. Le,M. Spielmann,Paolo Bruzzi,E. Montanaro,R. Rosso,M. R. Sertoli,M. Venturini,Dino Amadori,J. Benraadt,M. Kooi,A. O. van de Velde,J. A. van Dongen,J. B. Vermorken,Monica Castiglione,F. Cavalli,A. S. Coates,J. Collins,JF Forbes,Richard D. Gelber,A. Goldhirsch,J. Lindtner,Karen N. Price,C. M. Rudenstam,H.-J. Senn,Judith M Bliss,Clair Chilvers,R. C. Coombes,Emma Hall,Michel Marty,R. V. Borovik,G. Brufman,H. Hayat,E. Robinson,N. Wigler,Gianni Bonadonna,T. Camerini,G. De Palo,M. Del Vecchio,F. Formelli,Pinuccia Valagussa,A Martoni,F. Pannuti,G. Cocconi,A. Colozza,R. Camisa,K. Aogi,S. Takashima,T. Ikeda,K. Inokuchi,K. Sawa,H. Sonoo,S. Korzeniowski,J. Skolyszewski,M. Ogawa,J. Yamashita,J. Bonte,R. Christiaens,Robert Paridaens,W. Van den Boegart,P. Martin,S. Romain,T. Hakes,Clifford A. Hudis,R. Wittes,G. Giokas,D. Kondylis,B. Lissaios,R. de la Huerta,M. G. Sainz,R. Altemus,K. Cowan,David N. Danforth,Allen S. Lichter,Marc E. Lippman,Joyce A. O'Shaughnessy,Lori J. Pierce,Seth M. Steinberg,D. Venzon,JoAnne Zujewski,A. Paradiso,M. De Lena,F. Schittulli,J. Myles,J. L. Pater,Kathleen I. Pritchard,Stewart J. Anderson,G. Bass,Anna Brown,John Bryant,J. Costantino,James J. Dignam,Bernard Fisher,C Redmond,Sam Wieand,Norman Wolmark,I. M. Jackson,Mike K. Palmer,JN Ingle,Vera J. Suman,Nils-Olof Bengtsson,H. Jonsson,Lars-Gunnar Larsson,J. P. Lythgoe,M. Kissin,Bjørn Erikstein,E Hannisdal,A. B. Jacobsen,J. E. Varhaug,S. Gundersen,Martin Hauer-Jensen,H. Host,R. Nissen-Meyer,Roger W. Blamey,A. Mitchell,Morgan Da,J.F.R. Robertson,M. Di Palma,G. Mathe,J. L. Misset,R. M. Clark,Mitch Levine,K Morimoto,Y. Takatsuka,E. Crossley,Al Harris,Denis Talbot,Mark Taylor,B. di Blasio,V. Ivanov,Vladimir Semiglazov,J. Brockschmidt,M. R. Cooper,H. Ueo,Carla I. Falkson,Roger A'Hern,Stanley W. Ashley,T. J. Powles,Ian E. Smith,John Yarnold,J.-C. Gazet,N. Cocoran,N. Deshpande,L. di Martino,P. Douglas,A. Lindtner,G Notter,A. J. S. Bryant,G. H. Ewing,L. A. Firth,J. L. Krushen-Kosloski,L. Foster,W.D. George,Helen J. Stewart,P. Stroner,Per-Uno Malmström,Torgil Möller,Stefan Rydén,Ingrid Tengrup,Lena Tennvall-Nittby,J. Carstenssen,M. Dufmats,Thomas Hatschek,Bo Nordenskjöld,Martin Söderberg,John T. Carpenter,KS Albain,J. Crowley,Stuart A. Green,Silvana Martino,CK Osborne,Peter M. Ravdin,U. Glas,Ulla Johansson,L E Rutqvist,T. Singnomklao,Arne Wallgren,Rudolf Maibach,Beat Thürlimann,Hermann Brenner,A. Hercbergs,M Yoshimoto,Gerrit DeBoer,Alexander H.G. Paterson,JW Meakin,T. Panzarella,Y. Shan,Y. F. Shao,X. Wang,D. B. Zhao,Z. M. Chen,H. C. Pan,J. Bahi,M. Reid,M. Spittle,G. P. Deutsch,F. Senanayake,D. L. W. Kwong,Angelo Raffaele Bianco,Chiara Carlomagno,M. De Laurentiis,S. De Placido,Aman U. Buzdar,Tae C Smith,Jonas Bergh,Lars Holmberg,Göran Liljegren,Jan Nilsson,M. Seifert,P. Sevelda,C. C. Zielinsky,R. B. Buchanan,M. Cross,G.T. Royle,Janet A. Dunn,Robert Kerrin Hills,Michael Lee,J. M. Morrison,D. Spooner,A. Litton,Rowan T. Chlebowski,H. Caffier +412 more
TL;DR: The 10-year and 15-year effects of various systemic adjuvant therapies on breast cancer recurrence and survival are reported and it is found that the cumulative reduction in mortality is more than twice as big at 15 years as at 5 years after diagnosis.
Journal ArticleDOI
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials.
Mike Clarke,Rory Collins,Sarah C. Darby,C Davies,P. Elphinstone,V Evans,J Godwin,Richard Gray,C. Hicks,Spencer L. James,E MacKinnon,Paul McGale,T McHugh,Richard Peto,Carolyn W. Taylor,Yaochen Wang +15 more
TL;DR: It is found that variations in local treatment that substantially affect the risk of locoregional recurrence could also affect long-term breast cancer mortality, and that avoidance of a local recurrence in the conserved breast is recommended.
Journal ArticleDOI
Tamoxifen for early breast cancer: An overview of the randomised trials
TL;DR: The absolute improvement in recurrence was greater during the first 5 years, whereas the improvement in survival grew steadily larger throughout the first 10 years, and these benefits appeared to be largely irrespective of age, menopausal status, daily tamoxifen dose, and of whether chemotherapy had been given to both groups.
Journal Article
Polychemotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.
C. Focan,Seth M. Steinberg,M. Blichert-Toft,JF Forbes,Rory Collins,Stewart J. Anderson,R. Margreiter,C. S. Harwood,K. W. Andersen,G. Beighton,R. V. Borovik,EA Clarke,T Yasutomi,Walter Jonat,E. Mari,O. Abe,Richard Peto,Richard Gray,J. B. Vermorken,Bernard Asselain,Mitchell A Harris,Ingrid Tengrup,PC Lara,J.L. Laplanche,Sue Jackson,RJ Sylvester,H. Ueo,Pierre Fumoleau,R. Sauer,William C. Wood,Willi Sauerbrei,Rebecca Gelman,J. C. Redmond,Angelo Raffaele Bianco,Rodrigo Arriagada,M Hauer,Marie Overgaard,M. P. Cunningham,John L. Hayward,M. Kissin,Owen,W. Jack,Cooper,J. L. Pater,M. Ogawa,Jon Godwin,N Scorpiglione,Mike K. Palmer,H Johansen,H. Hayat,Aman U. Buzdar,Hyman B. Muss,H. Sonoo,David Riley,G. Brufman,MJ Piccart-Gebhart,John Bryant,R. Nissen,H. Koyama,J. Uchino,D. Parker,J Mace,M. Durand,G. Cocconi,Y. Morishita,CF Oliveira,R. L. Comis,A. Goldhirsch,M. Spielmann,J. E. Varhaug,Carsten Rose,J-B Bonte,A. R. Coates,C. S. McArdle,J. J. Price,Janet T. Powell,L. M. Vecchio,Martin Schumacher,Matthew Clarke,A. Nicolucci,Larry Norton,G. Mathe,H.H. Tooth,R. Huerta,A. Erazo Velásquez,Norman Wolmark,N. H. Gordon,Joan Houghton,Michael J. Baum,S. Gundersen,R. H. Creech,Gianni Bonadonna,D. C. Smith,R. J. Salmon,D.F. Hacking,R. C. Coombes,Kathleen I. Pritchard,Y. Lehingue,James J. Dignam,L. Mauriac,J. Myles,Sam Wieand,Spencer L. James,Carla I. Falkson,Carl Blomqvist,M. Belfiglio,H. L. Davis,AU Rubagotti,V. Gouon-Evans,K. Sawa,F. Pannuti,Francesco Boccardo,R. Abe,I.S. Fentiman,K. Sakai,T. M. Holdaway,Gloria Broadwater,Pinuccia Valagussa,M. G. Le,J. B. Dubois,Tae C Smith,J. Collins,M. Izuo,Manfred Kaufmann,C. K. Axelsson,Nancy E. Davidson,R Simon,AO de Lima,J. Yamashita,H. J. Trampisch,Jack Cuzick,S. Takashima,E. Robinson,G. Fountzilas,Lippman amp,Donna L. Berry,Henning T. Mouridsen,R. Wittes,A Kodric-Brown,R. M. Clark,D Jackson,N Corcoran,Umberto Veronesi,D. M. Dent,K Morimoto,C Davies,Y. Takatsuka,B Carstensen,Bernard Fisher,Lars-Gunnar Larsson,Cjh van de Velde,E. F. Lau,E. Greaves,P. Meier,Roger W. Blamey,John F. Forbes,Hma Yosef,R. Swindell,G. Bastert,Moïse Namer,JN Ingle,J. L. Misset,R. G. Kay,J. Benraadt,Christopher Hill,S. Romain,J. L. Haybittle,Karen N. Price,N. Wigler,R. Catalano,Judith M Bliss,Jfr Robertson,Lori J. Pierce,Vera J. Suman,Monica Castiglione,R D Rubens,H. Host,J. Albano,K. Kikuchi,A.J. Schauer,B. H. Mason,A Lewit-Bentley,Thierry Delozier,H.-J. Senn,Vilcoq,B Dil Blasio,T. Hakes,Douglass C. Tormey,J. Skolyszewski,K Welvaart,T. Tominaga,C. M. Rudenstam,JA Dongen,J. Costantino,S Bartholomeus,G. C. Mead,Michel Marty,Richard D. Gelber,M. Yoshida,McLaughlin,Mitch Levine,Joseph Ragaz,K. Enomoto,D Fournier,SB Schryver,V. J. Harvey,Udi Chetty,Y. Nomura,J. Lindtner,P. Forrest,N Cole Robert,Jacques Bonneterre,J. P. Lobelle,A. Bengry-Howell,P. Romestaing,I. C. Henderson,P Martin-Sanz,T. Palshof,G. C. Ribeiro,E Hannisdal,A. H. Gervasio,K. Sugimachi,Charles L. Shapiro,R. E. Crossley,C. Cirrincione,I. M. Jackson,Michael Gnant +226 more
TL;DR: The age-specific benefits of polychemotherapy appeared to be largely irrespective of menopausal status at presentation, oestrogen receptor status of the primary tumour, and of whether adjuvant tamoxifen had been given.
Journal ArticleDOI
Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials
Sarah C. Darby,Paul McGale,C Correa,Carolyn W. Taylor,R Arriagada,Mike Clarke,D Cutter,C Davies,Marianne Ewertz,Jon Godwin,Richard Gray,Lori J. Pierce,Timothy J. Whelan,Yaochen Wang,Richard Peto +14 more
TL;DR: In this paper, the authors conducted a meta-analysis of individual patient data for 10,801 women in 17 randomised trials of radiotherapy versus no radiotherapy after breast-conserving surgery, 8337 of whom had pathologically confirmed node-negative (pN0) or node-positive (nN+) disease.