Journal ArticleDOI
Prednisolone-induced diabetes mellitus in the cat: a historical cohort:
TLDR
Evaluating the frequency and investigate potential predisposing risk factors for the development of prednisolone-induced diabetes mellitus (PIDM) in cats found 12 out of 14 cats developed diabetes within 3 months of the initiation of therapy.Abstract:
ObjectivesPrednisolone is a commonly used drug in cats and potential adverse effects include hyperglycaemia and diabetes mellitus. The aims of this study were to evaluate the frequency and investig...read more
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Oral dexamethasone sodium phosphate solution significantly reduces pruritus and clinical lesions in feline hypersensitivity dermatitis: an open-label study
TL;DR: In this article, Dexamethasone sodium phosphate (DexSP, DexajectSP, Henry Schein; Dublin, OH, USA; 4 mg/mL), an intravenous glucocorticoid, can be absorbed by healthy cats when administered orally.
Journal ArticleDOI
Assessment of the possible causes of diabetes mellitus developed in patients post covid-19 treatment in a tertiary care hospital
TL;DR: It was found that both these categories of patients had comorbidities, and the development of this was seen between the 25th-40th day, and males were more prone than females.
Journal ArticleDOI
Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics.
TL;DR: In this article , the authors explored prior exposure to glucocorticoids or antibiotic treatment as risk factors for developing diabetes mellitus in dogs attending primary-care VetCompass clinics in the UK.
Journal ArticleDOI
Challenges in Differentiating Chronic Enteropathy from Low-Grade Gastrointestinal T-cell Lymphoma in Cats
TL;DR: In this paper , the end diagnosis is reached by combining clinical signs with gastrointestinal tract sampling for histology, immunohistochemistry, and molecular testing, with variable results depending on the laboratory used.
Journal ArticleDOI
Is methylprednisolone acetate-related insulin resistance preventable in cats?
Karine Marchioro Leal,Mariana Barcelos Rocha,Fernanda Varela,L. Rodrigues,Priscila Viau Furtado,Fernanda Vieira Amorim da Costa,Alan Gomes Pöppl +6 more
TL;DR: In this paper , a randomized clinical trial was conducted with 28 owned cats undergoing glucocorticoid therapy, where a single MPA dose of 20 mg intramuscularly was administered to each cat.
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Journal ArticleDOI
Pharmacokinetics and Pharmacodynamics of Systemically Administered Glucocorticoids
TL;DR: Simulations with a pharmacokinetic/pharmacodynamic model using T helper cell counts and endogenous Cortisol as biomarkers for the effects of methylprednisolone suggest that the clinical efficacy of low-dose glucocorticoid regimens might be increased with twice-daily glucocORTicoid administration.
Journal ArticleDOI
Glucose intolerance after renal transplantation depends upon prednisolone dose and recipient age.
Jøran Hjelmesæth,Anders Hartmann,Johan Kofstad,Jean Stenstrøm,Torbjørn Leivestad,Thore Egeland,Fauchald P +6 more
TL;DR: Increased prednisolone dose and older age are strongly associated with the development of posttransplant glucose intolerance.
Journal ArticleDOI
Glucocorticoid-induced hyperglycemia.
Antonio Pérez,Sergio Jansen-Chaparro,Ignasi Saigi,M. Rosa Bernal-Lopez,Inka Miñambres,Ricardo Gómez-Huelgas +5 more
TL;DR: In this article, the authors discuss the pathophysiology of corticosteroid-induced hyperglycemia and provide clues for diagnosis based on the duration of treatment and the administration schedule.
Journal ArticleDOI
Feline diabetes mellitus in the UK: the prevalence within an insured cat population and a questionnaire-based putative risk factor analysis
TL;DR: Gender was identified as the most important overall risk factor for the development of DM with low physical activity being the next most important risk factors for female cats and breed the nextmost important for male cats.
Journal ArticleDOI
Glucocorticoid-Induced Diabetes Mellitus: An Important but Overlooked Problem
Sunghwan Suh,Mi Kyoung Park +1 more
TL;DR: The treatment of GIDM should take into account the degree and pattern of hyperglycemia, as well as the type, dose, and schedule of glucocorticoid used, and it is essential to instruct the patient and/or the patient's family about how to perform the necessary adjustments.