Open Access
Presence of receptors for antigen and antibody on dengue virus-induced suppressor T cells and their products
Reads0
Chats0
TLDR
Dengue type 2 virus (DV)-induced suppressor pathway has a network of idiotype-anti-idiotype-like interactions which maintain the antigen specificity.Abstract:
Dengue type 2 virus (DV)-induced suppressor pathway consists of a cascade of Ts 1
cell and its product SF, Ts 2 cell and its product SF 2 and the Ts 3 cell which mediates antigen-specific suppression of humoral immune response. The present study was undertaken to investigate if the different constituents of this pathway have complementary receptors. It was observed that the suppressor activities of Ts 1 , SF and Ts 3 were abrogated by binding with anti-DV antibody while those of Ts 2 and SF 2 were abrogated by binding with DV antigen. Thus DV-induced suppressor pathway has a network of idiotype-anti-idiotype-like interactions which maintain the antigen specificity.read more
Citations
More filters
Book ChapterDOI
Togavirus-Induced Immunosuppression
TL;DR: The viruses included in the Togaviridae family are commonly known as ar boviruses that replicate in the tissues of arthropod and are transmitted to the vertebrate host by the bite of blood-sucking arthropods.