Rebecca E. Hussey

TL;DR: Given that T11 is the earliest T-lineage surface glycoprotein to appear in thymic ontogeny and is thus expressed before T3-Ti, the former may be involved in clonal expansion and/or differentiation during early development.

TL;DR: The development of monoclonal antibodies to such polymorphic T cell surface structures should provide important probes to further define the surface receptor for antigen.

TL;DR: Evidence is provided for a direct linkage between antigen recognition by T lymphocytes and surface expression of the T3 molecular complex, which inhibits cytotoxic T lymphocyte effector function by T4 and T8 clones as well as antigen-specific T cell recognition.

TL;DR: The findings demonstrate that antigen-induced proliferation is mediated through an autocrine pathway involving endogenous IL-2 production, release, and subsequent binding to IL-3-Ti receptor cross-linking.

TL;DR: Concentrations of soluble CD4 in the nanomolar range, like certain anti-CD4 monoclonal antibodies, inhibit syncytium formation and HIV infection by binding gp120-expressing cells, and class II specific T-cell interactions are uninhibited by solubleCD4 protein, whereas they are virtually abrogated by equivalent amounts of anti-T4 antibody.