Journal ArticleDOI
Prevalence of hyperprolactinemia in schizophrenic patients treated with conventional antipsychotic medications or risperidone.
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TLDR
Hyperprolactinemia is very prevalent among women and men treated with conventional antipsychotic medications or risperidone and should be seriously considered when choosing an antipsychotics suitable for the patient.About:
This article is published in Psychoneuroendocrinology.The article was published on 2003-04-01. It has received 337 citations till now. The article focuses on the topics: Risperidone & Schizophreniform disorder.read more
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Journal ArticleDOI
Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline
Shlomo Melmed,Felipe F. Casanueva,Andrew R. Hoffman,David L. Kleinberg,Victor M. Montori,Janet A. Schlechte,John A.H. Wass +6 more
TL;DR: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence for diagnosis and treatment of hyperprolactinemia.
Journal ArticleDOI
Gender Differences in Schizophrenia and First-Episode Psychosis: A Comprehensive Literature Review
TL;DR: Overall, gender differences have been found in a number of variables, and further study in this area could help provide useful information with a view to improving the care of these patients.
Journal ArticleDOI
Antipsychotic-induced hyperprolactinaemia: mechanisms, clinical features and management.
TL;DR: In patients prescribed antipsychotics who have biochemically confirmed hyperprolactinaemia it is important to exclude other causes of prolactin elevation, in particular tumours in the hypothalamic-pituitary area.
Journal ArticleDOI
Serious mental illness and physical health problems: a discussion paper.
Deborah Robson,Richard Gray +1 more
TL;DR: This discussion paper explores the complex reasons for these disparities in health, such as limitations of health services, the effects of having a serious mental illness, health behaviours and the effect of psychotropic medication.
Journal ArticleDOI
Circadian rhythms, sleep, and the menstrual cycle.
TL;DR: This paper reviews circadian rhythms in temperature, selected hormone profiles, and sleep-wake behavior in healthy women at different phases of the menstrual cycle, and indicates that the amplitude of other rhythms, such as melatonin and cortisol, may be blunted in the luteal phase.
References
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Journal ArticleDOI
Olanzapine versus placebo and haloperidol: Acute phase results of the North American double-blind olanzapine trial
Charles M. Beasley,Gary D. Tollefson,Pierre Tran,Winston Satterlee,Todd M. Sanger,Susan H. Hamilton +5 more
TL;DR: The most common treatment-emergent adverse events included somnolence, agitation, asthenia, and nervousness.
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Multiple fixed doses of “Seroquel” (quetiapine) in patients with acute exacerbation of schizophrenia: A comparison with haloperidol and placebo
Lisa A Arvanitis,B.G. Miller +1 more
TL;DR: Quetiapine is well tolerated and clinically effective in the treatment of schizophrenia and both superior to placebo and comparable to haloperidol in reducing positive symptoms at doses ranging from 150 to 750 mg/day and in reducing negative symptoms at a dose of 300mg/day.
Journal Article
Prolactin and Murine Mammary Tumorigenesis: A Review
TL;DR: If prolactin can be shown to influence human breast epithelium in a manner similar to its effect on rodent mammary tissue, then prophylactic and/of chemotherapeutic control of human breast tumorigenesis may be feasible by appropriate drug-mediated Prolactin suppression.
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Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects.
M. L. Huang,Achiel Van Peer,Robert Woestenborghs,Roland De Coster,Jos Heykants,Arno A I Jansen,Zbigniew Zylicz,Hendrik W Visscher,Jan H. G. Jonkman +8 more
TL;DR: It is concluded that risperidone metabolic polymorphism on increased plasma prolactin is minimal and that the active moiety is clinically relevant.
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Decreased bone density in hyperprolactinemic women
TL;DR: In women who present with secondary amenorrhea, anovulation, and galactorrhea, the chances of developing menopause are higher than in women who do not have any of these problems.