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Open AccessJournal ArticleDOI

Primary malignant melanoma of the oral cavity. A review of 177 cases

TLDR
The authors report six new cases of melanoma of the oral cavity and review 171 cases published since the last major review in 1975, including the classification of oral melanomas with radial growth phases.
Abstract
Malignant melanoma of the oral cavity is rare, accounting for about 1% to 8% of all melanomas. There have been no prospective studies of melanoma in this location, and all previous papers have reported small numbers of cases or have retrospectively reviewed case reports from the literature. The authors report six new cases and review 171 cases published since the last major review in 1975. The classification of oral melanomas with radial growth phases is discussed.

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Journal ArticleDOI

Primary mucosal malignant melanoma of the head and neck.

TL;DR: This study aims to assess the outcome and identify clinical and histologic prognostic indicators in a recent cohort of patients with MMHN treated at a single institution.
Journal ArticleDOI

Malignant mucosal melanoma of the head and neck: Review of the literature and report of 14 patients

TL;DR: In this paper, the authors conducted a retrospective review of 14 patients with characteristics similar to those in the literature in terms of outcome, and the 5-year survival rate for these patients was 14%.
Journal ArticleDOI

Oral mucosal melanoma : epidemiology and pathobiology

TL;DR: In the not too distant future, innovative retroviral transfection, antibodies against specific melanoma-associated factors, vaccination against melanoma, and gene therapy to repair cytogenetic abnormalities and tumor suppressor gene mutations may provide effective therapy and protection against melanomas.
Journal ArticleDOI

Primary mucosal melanoma

TL;DR: Primary mucosal melanomas are rare, biologically aggressive neoplasms and most afflicted individuals harbor micrometastatic disease and experience a course characterized by multiple local recurrences before the clinical development of distant disease.
Journal ArticleDOI

Mucosal melanoma of the nose and paranasal sinuses, a contemporary experience from the M. D. Anderson Cancer Center.

TL;DR: Sinonasal mucosal melanoma is a rare disease associated with a very poor prognosis and prognostic factors and outcomes with recent treatment modalities are sought.
References
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Journal Article

The Histogenesis and Biologic Behavior of Primary Human Malignant Melanomas of the Skin

TL;DR: Evidence is presented suggesting that superficial spreading melanoma and lentigo maligna melanoma (Hutchinson9s melanotic freckle) show a long period of superficial growth, followed by the relatively rapid appearance of nodules or deeper invasion within the primary lesion.
Journal ArticleDOI

Tumor thickness, level of invasion and node dissection in stage I cutaneous melanoma.

TL;DR: It was found that tumor thickness is a better measure of prognosis than is the level of invasion of the tumor, and the chance of developing recurrent disease appears to be directly proportional to tumor thickness.
Journal ArticleDOI

Ganglion cell populations in normal and pathological human cochleae. Implications for cochlear implantation.

TL;DR: The ganglion cell populations were largest in ears deafened by sudden deafness, Meniere's Disease, and ototoxic drugs; they were somewhat less for those with vascular occlusion, temporal bone fracture, otosclerosis, and cochlear dysplasias; and they were least in those with measles, bacterial labyrinthitis and congenital syphilis.
Journal Article

The developmental biology of primary human malignant melanomas.

TL;DR: The developmental biology of a primary neoplasm is illustrated by discussing and illustrating the evolution of these three dominant forms of melanoma: malignant melanoma of the superficial-spreading type, the lentigo-maligna type, and the nodular type.
Journal ArticleDOI

The classification of melanoma and its relationship with prognosis

TL;DR: Melanoma arising in nodular form is the most malignant and that arising in Hutchinson's melanotic freckle is the least malignant.
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