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Journal ArticleDOI

Prognostic significance of tumor grading and staging in mammary carcinomas with neuroendocrine differentiation

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TLDR
Multivariate analysis revealed that overall survival was predicted by tumor size, lymph node status, and proliferation rate as judged by Ki-67 immunohistochemistry, and only nodal status proved to be a significant independent prognostic factor for distant recurrence-free survival.
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This article is published in Human Pathology.The article was published on 2011-08-01. It has received 53 citations till now. The article focuses on the topics: Neuroendocrine differentiation & Carcinoma.

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Papillary and neuroendocrine breast lesions: the WHO stance.

TL;DR: In this paper, the authors highlight adaptations in the WHO 2012 classification of papillary and neuroendocrine breast lesions as compared with the previous 2003 version, and propose consensus criteria for distinguishing atypical ductal hyperplasia from ductal carcinoma in situ within an intraductal papilloma.
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Neuroendocrine Carcinoma of the Breast: Current Evidence and Future Perspectives

TL;DR: An accurate diagnosis of NECB is also important in the metastatic setting, in which a multimodality approach including specific therapies such as peptide receptor radionuclide therapy can be considered.
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Locally-advanced primary neuroendocrine carcinoma of the breast: case report and review of the literature.

TL;DR: The breast in situ component of primary neuroendocrine carcinoma of the breast may prevail on a core biopsy samples increasing the probability of underdiagnosing this tumor preoperatively.
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Invasive neuroendocrine carcinoma of the breast: a prognostic research of 107 Chinese patients.

TL;DR: NECs are more likely to be estrogen receptor(ER)/ progesterone receptor (PR) positive and human epidermal growth factor receptor 2 (HER-2) negative, and have a higher propensity for local recurrence and poorer overall survival(OS).
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Neuroendocrine breast tumours: breast cancer or neuroendocrine cancer presenting in the breast?

TL;DR: The literature search including the non-English literature identified 66 articles with data on 123 cases of neuroendocrine tumours of the breast, including the own, and best management remains unknown.
References
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Journal ArticleDOI

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up.

TL;DR: The results demonstrate that this method for histological grading provides important prognostic information and, if the grading protocol is followed consistently, reproducible results can be obtained.

Pathology and genetics

J. N. Eble
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