Journal ArticleDOI
Proline-catalyzed asymmetric reactions
Benjamin List,Benjamin List +1 more
About:
This article is published in Tetrahedron.The article was published on 2002-07-08. It has received 986 citations till now. The article focuses on the topics: Hajos–Parrish–Eder–Sauer–Wiechert reaction & Enamine.read more
Citations
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Asymmetric enamine catalysis.
Journal ArticleDOI
Asymmetric catalysis by chiral hydrogen-bond donors.
Mark S. Taylor,Eric N. Jacobsen +1 more
TL;DR: This review documents the structural and mechanistic features that contribute to high enantioselectivity in hydrogen-bond-mediated catalytic processes in small-molecule, synthetic catalyst systems.
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Asymmetric multicomponent reactions (amcrs): the new frontier
Diego J. Ramón,Miguel Yus +1 more
TL;DR: Asymmetric multicomponent reactions involve the preparation of chiral compounds by the reaction of three or more reagents added simultaneously and has some advantages over classic divergent reaction strategies, such as lower costs, time, and energy, as well as environmentally friendlier aspects.
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Asymmetric organocatalytic domino reactions.
TL;DR: This Minireview discusses the current development of domino reactions mediated by organocatalysts, as this principle is used very efficiently in the biosynthesis of complex natural products starting from simple precursors.
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Asymmetric Organocatalysis: From Infancy to Adolescence
TL;DR: This Review deals with selected studies reported in 2006 and the first half of 2007, and is intended to highlight four main aspects that may be taken as testimony of the present status and prospective of organocatalysis.
References
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Journal ArticleDOI
Proline-Catalyzed Direct Asymmetric Aldol Reactions
TL;DR: The finding that the amino acid proline is an effective asymmetric catalyst for the direct aldol reaction between unmodified acetone and a variety of aldehydes is reported.
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Reduction of Carbonyl Compounds with Chiral Oxazaborolidine Catalysts: A New Paradigm for Enantioselective Catalysis and a Powerful New Synthetic Method.
E. J. Corey,Christopher J. Helal +1 more
TL;DR: High enantioselectivity can be achieved when chiral oxazaborolidines are used as catalysts in the reduction of ketones by borane when the two reactants are activated and held in close proximity by the catalyst.
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Amino Acid Catalyzed Direct Asymmetric Aldol Reactions: A Bioorganic Approach to Catalytic Asymmetric Carbon-Carbon Bond-Forming Reactions
TL;DR: Direct asymmetric catalytic aldol reactions have been successfully performed using aldehydes and unmodified ketones together with commercially available chiral cyclic secondary amines as catalysts and the observed stereochemistry of the products is in accordance with the proposed transition state.