Journal ArticleDOI
Prophylaxis of influenza B with UK 2054.
P. N. Meenan,I.B. Hillary +1 more
TLDR
Combined results show a significant difference in favour of UK 2054 in the suppression of symptoms and signs prior to challenge with influenza virus B/England/13/65.About:
This article is published in The Lancet.The article was published on 1969-09-20. It has received 10 citations till now. The article focuses on the topics: Placebo.read more
Citations
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Journal ArticleDOI
Double-Blind Clinical Assessment of Ribavirin (Virazole) in the Prevention of Induced Infection with Type B Influenza Virus
Yasushi Togo,Elbert A. McCracken +1 more
TL;DR: Ribavirin suppressed signs and symptoms induced by influenza B challenge, but its effectiveness was marginal.
Book ChapterDOI
4 Antiviral Agents
TL;DR: This chapter explains that as the knowledge increases of the biochemical events that occur from the time a virus comes in contact with a host cell to when new viruses emerge from the same cell, it starts to find more ways of interrupting the process.
Journal ArticleDOI
Antiviral effect of 3, 4-dihydro-1-isoquinolineacetamide hydrochloride in experimental human rhinovirus infection.
TL;DR: The prophylactic DIQA therapy appears to suppress the cold syndrome and to reduce virus excretion, although its effect is marginal.
Journal ArticleDOI
Cyclooctylamine of Experimental in the Prevention Human Influenza
TL;DR: The prophylactic effectiveness of intranasally given SK&F 23880A (cyclooctylamine hydrochloride) against induced A 2 /Hong Kong influenza was evaluated in double-blind trials and was effective in preventing overt influenza in susceptible subjects.
Dissertation
An evaluation of test methods in the chemotherapy of influenza A virus infections
TL;DR: To establish the most suitable methods for detecting and quantitating anti-influenzal activity, a number of in vitro and in vivo systems were compared, and only amantadine hydrochloride and Ribavirin proved sufficiently active for further work.
References
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Journal ArticleDOI
Prophylaxis of influenza with a synthetic isoquinoline
TL;DR: When used prophylactically, the isoquinoline drug reduced by half the incidence of clinical illness and of virus infection when used against living influenza-B virus.