Journal ArticleDOI
Prostaglandins in fetal tracheal and amniotic fluid from late pregnant sheep
TLDR
The levels of prostaglandins in these fluids were similar in ewes bearing hypophysectomized fetuses, and there was no correlation between the level of prostglandins found in each fluid.About:
This article is published in Prostaglandins.The article was published on 1977-11-01. It has received 15 citations till now. The article focuses on the topics: Amniotic fluid & Prostaglandins F.read more
Citations
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Book ChapterDOI
Initiation of parturition.
TL;DR: The pendulum swung decisively away from maternal control towards fetal control and the fetal endocrine system became the focus of attention of most investigators.
Journal ArticleDOI
Early changes in prostaglandin concentrations in ovine maternal and fetal plasma, amniotic fluid and from dispersed cells of intrauterine tissues before the onset of ACTH-induced pre-term labour.
TL;DR: The results imply a causal relationship between rising PG and later myometrial contractions, rather than PG changes resulting from enhanced uterine activity, and there is a selective increase in plasma PGF-2 alpha concentrations before the onset of delivery.
Journal ArticleDOI
Gestational changes in prostanoid concentrations in intrauterine tissues and fetal fluids from pregnant sheep, and the relation to prostanoid output in vitro.
TL;DR: Results indicate that prostanoid production by fetal and maternal intrauterine tissues is, in general, lower on Day 50 than at the other times of pregnancy studied.
Journal ArticleDOI
Uterine Prostaglandin Concentrations in Sheep during Late Pregnancy and Adrenocorticotropin-Induced Labor
TL;DR: Analysis of variance indicated a significant effect of uterine area on PG concentrations, and the areas of highest PG concentrations were cotyledons and chorioallantois, suggesting that these may be major sites of synthesis.
Journal ArticleDOI
Prostanoid concentrations in maternal/fetal plasma and amniotic fluid and intrauterine tissue prostanoid output in relation to myometrial contractility during the onset of adrenocorticotropin-induced preterm labor in sheep.
TL;DR: PGs increase in all fluids before the increase in uterine mechanical activity during induced preterm labor, implying that PGs mediate this event and are not a result of the administration of P-ACTH.
References
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Book ChapterDOI
The mechanism of initiation of parturition in the ewe.
TL;DR: In this article, the authors discuss the mechanism of initiation of parturition in the ewe and describe a study that has been carried out on sheep to determine the extent to which the lamb shares in the mechanisms of initiation, to elucidate the means of its participation, and to unravel the intricate endocrine relationship between the conceptus and the mother.
Journal ArticleDOI
Prostaglandin content of amniotic fluid during pregnancy and labour
Sultan M. M. Karim,Jean Devlin +1 more
TL;DR: A total of 38 individual specimens of amniotic fluid obtained at various stages of pregnancy and during labour were investigated for presence of prostaglandins, finding that they are formed in the cells of the decidua.
Journal ArticleDOI
Prostaglandins in the circulation of the fetal lamb.
TL;DR: There was a significant decrease in the concentration of PGE and PGF in the plasma of lambs within 12 h after birth compared to the levels found in the same animals as fetuses a few hours previously.
Journal Article
Initiation of human parturition. I. Mechanism of action of arachidonic acid.
Paul C. MacDonald,F. M. Schultz,Johann H. Duenhoelter,Norman F. Gant,Juan M. Jimenez,Jack A. Pritchard,John C. Porter,John M. Johnston +7 more
TL;DR: Arachidonate injection as a mechanism for the initiation of labor in humans is proposed on the basis of observations from women in labor and from women not in labor.
Journal ArticleDOI
E prostaglandins in amniotic fluid during late pregnancy and labour.
TL;DR: Concentrations of prostaglandins e1 and E2 (PGE1 and PGE2) have been measured by gas liquid chromatography with electron‐capture detection, in samples of amniotic fluid from 49 patients with normal pregnancies and one patient with a pregnancy complicated by anencephaly.