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Open AccessJournal ArticleDOI

Pulsatile perfusion versus conventional high-flow nonpulsatile perfusion for rapid core cooling and rewarming of infants for circulatory arrest in cardiac operation

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TLDR
Thirty consecutive infants undergoing hypothermia and circulatory arrest for repair of ventricular septal defect, transposition of the great vessels, or atrioventricular canal defects were alternately selected for conventional high flow nonpulsatile perfusion or pulsatile perfusions during core cooling and rewarming to suggest that pulsatile perfume is safe and is more rapid and physiological than conventional high-flow nonpulse perfusion.
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This article is published in The Journal of Thoracic and Cardiovascular Surgery.The article was published on 1979-11-01 and is currently open access. It has received 52 citations till now. The article focuses on the topics: Pulsatile flow & Perfusion.

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Citations
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Journal ArticleDOI

Pulsatile and nonpulsatile cardiopulmonary bypass: review of a counterproductive controversy.

TL;DR: Failure to quantitate adequately the pulsatile components of flow in these studies prevents differentiation between effective and ineffective forms of pulsatile flow and makes comparison of studies difficult.
Journal ArticleDOI

Primary repair of interrupted aortic arch and severe aortic stenosis in neonates.

TL;DR: Two infants, aged 36 days old and 18 days old, with interrupted aortic arch types B and A, respectively, and with severeAortic stenosis, were successfully operated on by use of pulsatile cardiopulmonary bypass, revealing satisfactory anatomical and hemodynamic results in both cases.
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Brain tissue pH, oxygen tension, and carbon dioxide tension in profoundly hypothermic cardiopulmonary bypass. Comparative study of circulatory arrest, nonpulsatile low-flow perfusion, and pulsatile low-flow perfusion.

TL;DR: It is concluded that a 120-minuteperiod of nonpulsatile low-flow perfusion provides more protection from brain damage than a 60-minute period of circulatory arrest and pulsatile flow will increase the safety margin of cardiopulmonary bypass even if the flow rate is reduced to 25 ml/kg/min.
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Defining Pulsatile Perfusion: Quantification in Terms of Energy Equivalent Pressure

TL;DR: This definition establishes common criteria for assessment of the effectiveness of extracorporeal support and contains both the arterial pressure and pump flow rate, which are the 2 most critical parameters for open heart surgery.
References
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Journal ArticleDOI

Intracardiac surgery in neonates and infants using deep hypothermia with surface cooling and limited cardiopulmonary bypass.

TL;DR: Thirty-three of 37 infants under 10 kg in weight, with correctable lesions, survived this procedure, including 25 aged 8 days to 12 months, and is believed to have wide application in the neonatal and infant group.
Journal ArticleDOI

Energy equivalent pressure.

TL;DR: In this article, the authors describe differences in steady and pulsatile blood flow in terms of an energy equivalent pressure, which is obtained by calculation from phasic flow and pressure measurements.
Journal ArticleDOI

Hemodynamic, metabolic, and hematologic effects of pulsatile cardiopulmonary bypass.

TL;DR: Cardiopulmonary bypass with pulsatile flow was found to offer the following statistically significant advantages: lower systemic vascular resistance (p) and lower systemicascular resistance (r) during extracorporeal circulation.
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