Quantitative Angiocardiography IV. Relationships of Left Atrial and Ventricular Pressure and Volume in Mitral Valve Disease
TLDR
Quantitative angiocardiographic methods have been used to determine left ventricular volume andLeft ventricular mass (LVM) in 100 patients with isolated mitral valve disease and the data are presented with cumulative distribution curves suitable for reference standards.Abstract:
Quantitative angiocardiographic methods have been used to determine left ventricular volume and left ventricular mass (LVM) in 100 patients with isolated mitral valve disease. Thirty-six patients had mitral stenosis (MS), 29 had mitral regurgitation (MR), and 35 had combined stenosis and regurgitation (MS + MR). Data on volume and LVM from these patients are presented and are related to standard flow and intracardiac pressure determinations and compared with normal values. In patients with MS, the mean end-diastolic volume per square meter of body surface area (EDV/m2) was 72 ml/m2 and was increased to 148 ml/m2 in those with MR. EDV/m2 correlated closely with the severity of regurgitation and less well with LV end-diastolic pressure. The mean LV stroke volume was slightly smaller than normal in patients with MS (38 ml/m2) and was greatly increased in those with MR (88 ml/m2). The LV stroke volume correlated closely with the severity of regurgitation, r = 0.928. The ejection fraction (EF) was low in 37% of patients with MS and in 22% of those with MS + MR and MR alone. Left atrial volume was larger than normal in all patients and, although generally larger in those with regurgitation, did not correlate with its severity. In contrast, cyclic left atrial volume change was correlated with the severity of mitral regurgitation, r = 0.785. The data are presented with cumulative distribution curves suitable for reference standards.read more
Citations
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Left Atrial Size: Physiologic Determinants and Clinical Applications
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References
More filters
Journal ArticleDOI
Hydraulic formula for calculation of the area of the stenotic mitral valve, other cardiac valves, and central circulatory shunts. I
Richard Gorlin,S.G. Gorlin +1 more
TL;DR: Standard hydrokinetic orifice formulas applied to stenotic mitral, pulmonic, tricuspid, and aortic valves, patent ductus arteriosus, and atrial and ventricular septal defects present an objective evaluation of surgical procedures designed to widen stenotic orifices or to abolish abnormal shunts.
Journal ArticleDOI
A method for determining left ventricular mass in man.
TL;DR: Values for left ventricular mass were calculated from the biplane x-ray films and were demonstrated to agree closely with directly measuredLeft ventricular weights on postmortem human hearts.
Journal ArticleDOI
Quantitative angiocardiography. I. The normal left ventricle in man.
TL;DR: The ventricular volumes did not correlate well with age, sex, body surface area, or weight, but correlated in a negative manner with heart rate, and there was a significant difference between left ventricular wall thickness and mass in normal men and women.
Journal ArticleDOI
The Estimation of Probability Densities and Cumulatives by Fourier Series Methods
Richard A. Kronmal,M. Tarter +1 more
TL;DR: In this paper, a class of estimators of the probability density function f and the associated cumulative distribution function F are considered and simple expressions for the mean integrated square errors, M.I.S.E.
Journal ArticleDOI
Quantitation of valvular insufficiency in man by angiocardiography.
Harold Sandler,Harold Sandler,Harold T. Dodge,Harold T. Dodge,Robert E. Hay,Robert E. Hay,Charles E. Rackley,Charles E. Rackley +7 more
TL;DR: In 15 subjects, aortic or mitral valve orifice sizes as calculated from a comparison of left ventricular stroke volume and forward flow per stroke agreed closely with findings at operation or postmortem examination.
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