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Quantitative study of infarcted myocardium in cardiogenic shock.

C Harnarayan, +3 more
- 01 Nov 1970 - 
- Vol. 32, Iss: 6, pp 728-732
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TLDR
A post-mortem study of the heart was performed in 20 patients dying of cardiogenic shock finding extensive myocardial injury predominantly affecting the left ventricle and the interventricular septum.
Abstract
A post-mortem study of the heart was performed in 20 patients dying of cardiogenic shock. The extent of infarcted myocardium was defined by using a mitochondrial dehydrogenase stain nitro-BT which allowed macroscopical recognition of tissue death as early as 12 hours. Extensive myocardial injury was found to accompany cardiogenic shock predominantly affecting the left ventricle and the interventricular septum. Severe atheromatous involvement of the coronary arteries was noted.

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Citations
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Effect of infarct size limitation by propranolol on ventricular arrhythmias after myocardial infarction.

TL;DR: It is shown that pretreatment with propranolol was able to achieve significant infarct size reduction in this particular animal model of LAD occlusion followed by reperfusion through a critical stenosis, and that pharmacologic limitation of infarCT size may preserve viable but potentially jeopardized areas of myocardium.
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Right Ventricular Infarction: Contribution of Echocardiography to Diagnosis and Management.

TL;DR: Serial two‐dimensional echocardiography and Doppler are also valuable in short‐ and long‐term management, to detect complications, and to assess outcome.
Journal ArticleDOI

Intra-aortic balloon pumping for low cardiac output syndromes.

TL;DR: Since the prototype of the intra-aortic balloon pump was introduced, data accumulated from work with animals and in humans have begun to establish those clinical conditions amenable to partial temporary circulation support and to define the physiologic limits of this support system.
Journal ArticleDOI

Limitation of myocardial infarct size: review of experimental basis and clinical trials.

TL;DR: Review of the experimental basis for the concept indicates that although manipulation of the ST segment of the electrocardiogram is not sufficient proof that myocardial necrosis can be limited, more robust experimental methods have confirmed the efficacy of a variety of interventions in experimental coronary occlusion.
Journal ArticleDOI

Mechanical circulatory assistance by intra-aortic balloon pumping for the treatment of cardiogenic shock.

TL;DR: With IABP catheterization studies performed in these critically-ill patients are well tolerated, and some attempt to correct the underlyng anatomic abnormalities (reversible ischaemic areas and/or mechanical defects) appears necessary if these patients are to sruvive.
References
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Journal ArticleDOI

Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients

TL;DR: The results of treatment of 250 patients with established acute myocardial infarction in a coronary care unit in a university hospital are described in this article, where a classification of functional severity based on clinical evidence of heart failure or shock is presented.
Journal ArticleDOI

Quantitative methods in the study of pulmonary pathology.

M. S. Dunnill
- 01 Dec 1962 - 
TL;DR: The purpose of this paper is to show how the methods of quantitation as applied to the lung, but the methods mentioned are capable of adaptation to almost any organ.
Journal ArticleDOI

The Coronary Care Unit: New Perspectives and Directions

TL;DR: In the past two decades there have been momentous advances in the care of patients with cardiovascular ailments, yet, mortality from coronary-artery disease has remained unaffected, with 65% of deaths occurring in the initial three days and 85% during the first week of attack.
Journal ArticleDOI

A coronary-care unit in the routine management of acute myocardial infarction

TL;DR: The design, equipment and staffing of the six-bedded coronary-care unit at the Royal-Infirmary, Edinburgh are described and a high proportion were due to causes such-as shock, asystole and severe cardiac failure, which at-present are mostly irremediable.
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