J
John Ross
Researcher at University of California, San Diego
Publications - 260
Citations - 28923
John Ross is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Myocardial infarction & Heart failure. The author has an hindex of 91, co-authored 258 publications receiving 28177 citations. Previous affiliations of John Ross include Scripps Health & University of Vienna.
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Journal ArticleDOI
Factors Influencing Infarct Size Following Experimental Coronary Artery Occlusions
Peter R. Maroko,John K. Kjekshus,Burton E. Sobel,Tan Watanabe,James W. Covell,John Ross,Eugene Braunwald +6 more
TL;DR: It is concluded that the hemodynamic status and neurohumoral background at the time of occlusion and for up to 3 hr thereafter can alter the extent and severity of myocardial ischemic injury andMyocardial necrosis.
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Cardiac Muscle Cell Hypertrophy and Apoptosis Induced by Distinct Members of the p38 Mitogen-activated Protein Kinase Family
Yibin Wang,Shuang Huang,Valerie P. Sah,John Ross,Joan Heller Brown,Jiahuai Han,Kenneth R. Chien +6 more
TL;DR: The direct involvement of p38 pathways in cardiac hypertrophy and apoptosis suggests a significant role for p38 signaling in the pathophysiology of heart failure.
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MLP-Deficient Mice Exhibit a Disruption of Cardiac Cytoarchitectural Organization, Dilated Cardiomyopathy, and Heart Failure
Silvia Arber,John J. Hunter,John Ross,Minoru Hongo,Gilles Sansig,Jacques Borg,Jean-Claude Perriard,Kenneth R. Chien,Pico Caroni +8 more
TL;DR: In vivo analysis revealed that MLP-deficient mice reproduce the morphological and clinical picture of dilated cardiomyopathy and heart failure in humans, providing the first model for this condition in a genetically manipulatable organism.
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Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy
Howard A. Rockman,Robert S. Ross,Adrienne N. Harris,Kirk U. Knowlton,Mark E. Steinhelper,Loren J. Field,John Ross,Kenneth R. Chien +7 more
TL;DR: Evidence is provided that atrial-specific and inducible expression of the atrial natriuretic factor gene can be segregated, suggesting that a distinct set of regulatory cis sequences may mediate the up-regulation of the ANF gene during in vivo pressure overload hypertrophy.
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Regional Myocardial Function during Acute Coronary Artery Occlusion and Its Modification by Pharmacologic Agents in the Dog
TL;DR: The results indicate the power of this approach, which provides continuous quantification of regional wall function in myocardial ischemia and during therapeutic interventions, and suggests a protective effect of this drug.