Journal ArticleDOI
Quinolone antibiotic with potential to photosensitize skin tumorigenesis.
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This article is published in Journal of Photochemistry and Photobiology B-biology.The article was published on 1997-02-01. It has received 67 citations till now.read more
Citations
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Journal ArticleDOI
Drug-induced cutaneous photosensitivity: incidence, mechanism, prevention and management.
TL;DR: Some recent studies suggest that diet supplementation with antioxidants may be beneficial in increasing the minimum erythemal UV radiation dose and prevention of photosensitivity involves adequate protection from the sun with clothing and sunscreens.
Journal ArticleDOI
Fluoroquinolone antibacterials enhance UVA-induced skin tumors
TL;DR: All the fluoroquinolone antibiotics studied have the capability of enhancing UVA-induced phototumorigenesis, but only lomefloxacin caused the development of cystic squamous cell carcinomas in the majority of treated animals.
Journal ArticleDOI
Quinolone antibacterials: a new class of photochemical carcinogens
TL;DR: Fluoroquinolones warrant further study, because they have potential photocarcinogenic properties, and an increase in the number of benign skin tumors when compared with animals exposed to UVA alone.
Journal ArticleDOI
Photosensitised pyrimidine dimerisation in DNA
TL;DR: In this paper, the authors focus on cyclobutane pyrimidine (Pyridine) dimers, which are by far the most relevant Pyr photoproducts obtained by sensitisation.
References
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Journal ArticleDOI
Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.
TL;DR: Oral administration of a photoactive drug, 8-methoxypsoralen (methoxsalen), followed by exposure to a high-intensity, longwave ultraviolet-light system resulted in complete clearing of generalized psoriasis in 21 patients.
Journal Article
Wavelength Dependence of Skin Cancer Induction by Ultraviolet Irradiation of Albino Hairless Mice
F.R. de Gruijl,Henricus J. C. M. Sterenborg,Paul Donald Forbes,Ronald E. Davies,Curtis Cole,Gert Kelfkens,H. van Weelden,H. Slaper,J.C. van der Leun +8 more
TL;DR: The large variation in tumor responses in the present data set can be transformed to a coherent, common dose-response relationship by proper spectral weighting with this single action spectrum.
Journal ArticleDOI
Cutaneous squamous-cell carcinoma in patients treated with PUVA.
Robert S. Stern,Nan M. Laird,John W. Melski,John A. Parrish,Thomas B. Fitzpatrick,Howard L. Bleich +5 more
TL;DR: After adjustment for exposures to ionizing radiation and topical tar preparations, the risk that cutaneous squamous-cell carcinoma would develop at least 22 months after the first exposure to PUVA was 12.8 times higher in patients exposure to a high dose than in those exposed to a low dose.
Journal ArticleDOI
The carcinogenic risk of treatments for severe psoriasis
Robert S. Stern,Nan M. Laird +1 more
TL;DR: A small number of patients with severe psoriasis have responded to treatment with methotrexate, and these therapies are often used for prolonged periods and may be carcinogenic.
BookDOI
The Science of photomedicine
James D. Regan,John A. Parrish +1 more
TL;DR: Presented at the 7th Annual Meeting of the American Society for Photobiology, June 24-28, Pacific Grove, California.