Journal ArticleDOI
Reaction of Chlorotrimethylsilane with Some Cholestane Derivatives
Mubarak Husain,Haseem Hasan Khan +1 more
TLDR
In this article, a method for synthesis of 6-ones and chlorohydrins along with the synthesis of π-chloro-oximes have been achieved, which can be used either directly or in combination with a suitable metal.About:
This article is published in Synthetic Communications.The article was published on 1981-01-01. It has received 7 citations till now. The article focuses on the topics: Cholestane & Chlorohydrins.read more
Citations
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Journal ArticleDOI
Abnormal Beckmann rearrangement of steroidal α-chlorocyclobutanone oximes: the fragmentation–substitution reaction
TL;DR: In contrast to the Beckmann rearrangement of the α-unsubstituted oximes, α-chlorocyclobutanone oximes on treatment with thionyl chloride in benzene gave normal and abnormal reaction products.
Journal ArticleDOI
Circular dichroism of steroidal and related cisoid α,β-unsaturated ketones. Part II
TL;DR: In this article, the relation between structure and observed Cotton effects (CE's) depending on the solvent or the temperature has been discussed in terms of previously published rules (Part I), and it is also shown that CD spectra of these compounds are influenced by substituents located in the allylic axial or equatorial as well as α′-axial position.
Journal ArticleDOI
Reaction of Nitrosyl Chloride Gas with Unsaturated Steroids
TL;DR: In this article, the structures of these compounds were established on the basis of their spectral properties, and some pertinent chemical transformations were discussed for the formation of some unusual products are discussed.
Patent
New cholest-4-en-3-one oxime derivatives, pharmaceutical compositions comprising them, and preparation process
Cyrille Drouot,Delphine Maux +1 more
TL;DR: In this paper, the authors defined a new compound of the formula (I) in which X represents an oxygen atom or an =N-OH group and R represents a group selected from (II) or one of its esters and/or its addition salts with pharmaceutically acceptable acids.
Patent
Use of new and known 4-cholesten-3-one oxime derivatives as medicaments, especially neuroprotective medicaments
Cyrille Drouot,Delphine Maux +1 more
TL;DR: In this article, a 4-cholesten-3-one oxime derivatives of formula (I) and their acid addition salts are used as medicaments and a positive effect of 3-hydroxyimino-4 cholestensen-6-one on the survival of bone-marrow motoneurons at a concentration of 3 mu M is reported.
References
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Journal ArticleDOI
A Study of the Mechanism of Conversion of Acetate to Cholesterol via Squalene1
Journal ArticleDOI
THE STEREOCHEMISTRY OF THE i-STEROIDS AND THEIR TRANSFORMATION PRODUCTS
R. M. Dodson,Byron Riegel +1 more
Journal ArticleDOI
Silyl nitronates: improved nitro-aldol reactions and reductive routes to 2-aminoalcohols
Ernest W. Colvin,Dieter Seebach +1 more
TL;DR: In this article, the preparation of silyl nitronates from both primary and secondary nitroalkanes, their fluoride-ion catalysed reaction with carbonyl compounds, and the ready lithium aluminium hydride reduction of the soformed protected nitro-alcohols to 2-aminoalcohols are described.