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Journal ArticleDOI

Recent Trend in New Pesticides Containing Fluorine

TLDR
In this paper, major physico-chemical impacts resulting from the incorporation of fluorine atom into hydrocarbon moiety of organic molecules are briefly described in alternate reference to its unique electronic features and various physical parameters essential with recent structure-activity studies, some of which are discussed respectively as active examples of pesticide developments on the basis of quantitative structureactivity relationship.
Abstract
Firstly, major physico-chemical impacts resulting from the incorporation of fluorine atom into hydrocarbon moiety of organic molecules are briefly described in alternate reference to its unique electronic features and various physical parameters essential with recent structure-activity studies, some of which are discussed respectively as active examples of pesticide developments on the basis of quantitative structure-activity relationship. Then, a number of new or important fluorine chemistry are introduced as useful tool for synthesis of pesticide molecules having fluorine atom. Finally, 24 of selected examples of fluorine containing pesticides of mostly late issue are compiled in view of visualizing the recent R & D trend.

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Citations
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Journal ArticleDOI

New Electrophilic Trifluoromethylating Agents.

TL;DR: These novel electrophilic trifluoromethylating agents react under mild conditions with a variety of aromatic rings (p-hydroquinone, pyrrole, and aniline) to give triflorometHylated compounds in moderate to high yields.
Journal ArticleDOI

Facile syntheses of fluorine-containing α,β-unsaturated acids and esters from 2-trifluoromethylacrylic acid

TL;DR: In this paper, various types of fluorine-containing α,β-unsaturated acids and their esters were synthesized from 2-trilfuoromethylacrylic acid as a sole starting material.
Journal ArticleDOI

α-(Trifluoromethyl)amine Derivatives via Nucleophilic Trifluoromethylation of Nitrones

TL;DR: Nitrones with alkyl groups bound directly to the 1,3-dipolar moiety fail to react with TMSCF(3), but trifluoromethylation of beta,gamma-unsaturated nitrones followed by reduction of the double bond can circumvent this limitation.
Book ChapterDOI

Biologically Active Organofluorine Compounds

TL;DR: One of the important applications of fluorinated organic compounds is in medicinal chemistry as mentioned in this paper, and recent progress in organofluorine chemistry has contributed significantly to the great advances in modern medical treatments.
References
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Journal ArticleDOI

Substituent constants for correlation analysis.

TL;DR: Swain and Lupton's gamma and kappa values have been calculated from the omego constants for pi and omega for a miscellaneous group of aromatic substituents of interest to medicinal chemists.
Book

Chemistry of Pesticides

TL;DR: This chapter discusses pesticides formulations, inorganic pesticides, and their derivatives, andderivatives of sulfuric and sulfurous acids.