Journal ArticleDOI
Recommendations for using regenerative endodontic procedures in permanent immature traumatized teeth.
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TLDR
The lack of long-term evidence to support the use of regenerative endodontic procedures in traumatized teeth with open apices means that revascularization regeneration procedures should only be attempted if the tooth is not suitable for root canal obturation, and after apexogenesis, apexification, or partial pulpotomy treatments have already been attempted and have a poor prognosis.Abstract:
The regeneration of immature permanent teeth following trauma could be beneficial to reduce the risk of fracture and loss of millions of teeth each year. Regenerative endodontic procedures include revascularization, partial pulpotomy, and apexogenesis. Several case reports give these procedures a good prognosis as an alternative to apexification. Care is needed to deliver regenerative endodontic procedures that maintain or restore the vitality of teeth, but which also disinfect and remove necrotic tissues. Regeneration can be accomplished through the activity of the cells from the pulp, periodontium, vascular, and immune system. Most therapies use the host's own pulp or vascular cells for regeneration, but other types of dental stem cell therapies are under development. There are no standardized treatment protocols for endodontic regeneration. The purpose of this article is to review the recent literature and suggest guidelines for using regenerative endodontic procedures for the treatment of permanent immature traumatized teeth. Recommendations for the selection of regenerative and conventional procedures based on the type of tooth injury, fracture type, presence of necrosis or infection, periodontal status, presence of periapical lesions, stage of tooth development, vitality status, patient age, and patient health status will be reviewed. Because of the lack of long-term evidence to support the use of regenerative endodontic procedures in traumatized teeth with open apices, revascularization regeneration procedures should only be attempted if the tooth is not suitable for root canal obturation, and after apexogenesis, apexification, or partial pulpotomy treatments have already been attempted and have a poor prognosis.read more
Citations
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Journal ArticleDOI
Treatment options: biological basis of regenerative endodontic procedures
TL;DR: The current literature supporting a biological rationale for considering regenerative endodontic treatment procedures in treating the immature permanent tooth with pulp necrosis is summarized.
Journal ArticleDOI
Revascularization: a treatment for permanent teeth with necrotic pulp and incomplete root development.
Ronald Wigler,Arieh Y. Kaufman,Shaul Lin,Shaul Lin,Nelly Steinbock,Hagai Hazan-Molina,Calvin D. Torneck +6 more
TL;DR: Although the outcome of revascularization procedures remains somewhat unpredictable and the clinical management of these teeth is challenging, when successful, they are an improvement to treatment protocols that leave the roots short and the walls of the root canal thin and prone to fracture.
Journal ArticleDOI
Revascularization Outcomes: A Prospective Analysis of 16 Consecutive Cases
Bill Kahler,Sonali Mistry,Alex J. Moule,Andrew K. Ringsmuth,Peter Case,Andrew Thomson,Trevor Holcombe +6 more
TL;DR: Preliminary outcomes of regenerative endodontic procedures carried out on 16 teeth, 3 mandibular premolars and 13 traumatized central incisors, after 18-month reviews showed patterns of continued root maturogenesis were variable, with unaesthetic results in 10 of the 16 cases.
Journal Article
Revascularization Outcomes: A Prospective Analysis of 16 Consecutive Cases (vol 40, pg 333, 2014)
Bill Kahler,Sonali Mistry,Alex J. Moule,Andrew K. Ringsmuth,Peter Case,Andrew Thomson,Trevor Holcombe +6 more
TL;DR: In this paper, a prospective clinical study reports on preliminary outcomes of regenerative endodontic procedures carried out on 16 teeth, 3 mandibular premolars and 13 traumatized central incisors, after 18-month reviews.
Journal ArticleDOI
Regenerative Endodontics: Barriers and Strategies for Clinical Translation
Jeremy J. Mao,Sahng G. Kim,Jian Zhou,Ling Ye,Shoko Cho,Takahiro Suzuki,Susan Y. Fu,Rujing Yang,Xuedong Zhou +8 more
TL;DR: Recent work using novel biomaterial scaffolds and growth factors that orchestrate the homing of host endogenous cells represents a departure from traditional cell transplantation approaches and may accelerate clinical translation in regeneration endodontics.
References
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Journal ArticleDOI
Regenerative endodontics: a review of current status and a call for action.
TL;DR: An overview of the methodological issues required to develop potential regenerative endodontic therapies is provided, and a call for action is presented to develop these therapies for clinical use.
Journal ArticleDOI
Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture.
TL;DR: The results indicate that the fracture strength of calcium hydroxide-filled immature teeth will be halved in about a year due to the root filling, which may explain the frequent reported fractures of immature teeth filled with calcium Hydroxide for extended periods.
Journal ArticleDOI
Revascularization of Immature Permanent Teeth With Apical Periodontitis: New Treatment Protocol?
Francisco Banchs,Martin Trope +1 more
TL;DR: In this paper, a new technique was presented to revascularize immature permanent teeth with apical periodontitis, where the canal is disinfected with copious irrigation and a combination of three antibiotics.
CLINICAL RESEARCH Revascularization of Immature Permanent Teeth With Apical Periodontitis: New Treatment Protocol?
Francisco Banchs,Martin Trope +1 more
TL;DR: In this case, the combination of a disinfected canal, a matrix into which new tissue could grow, and an effective coronal seal appears to have produced the environment necessary for successful revascularization.
Journal ArticleDOI
Revascularization of an immature permanent tooth with apical periodontitis and sinus tract.
TL;DR: Thickening of the canal wall and complete apical closure was confirmed 30 months after the treatment, indicating the revascularization potential of a young permanent tooth pulp into a bacteria-free root canal space.
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Revascularization of Immature Permanent Teeth With Apical Periodontitis: New Treatment Protocol?
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