Open AccessJournal Article
Reduced bone mass and altered growth plate morphology in aged rats exposed to intrauterine protein restriction
G. Mehta,Helmtrud I. Roach,Simon C. Langley-Evans,Patrick R. Taylor,Richard O.C. Oreffo,Avan Aihie Sayer,Clarke Nmp.,Cyrus Cooper +7 more
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This article is published in Journal of Bone and Mineral Research.The article was published on 2001-01-01 and is currently open access. It has received 3 citations till now.read more
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Maternal protein deficiency affects mesenchymal stem cell activity in the developing offspring
TL;DR: In this article, the authors used a rat model of maternal protein insufficiency to investigate the cellular mechanisms involved in the programming of bone development and found that normal proliferation and differentiation of mesenchymal stem cells were delayed by maternal protein restriction during early life.
Journal Article
The fetal origins of peak bone mass: Maternal protein deficiency affects mesenchymal stem cell activity in the developing offspring.
TL;DR: Normal proliferation and differentiation of mesenchymal stem cells were delayed by maternal protein restriction during early life and may represent an important candidate mechanism for the programming of osteoporosis and associated consequences in later life.
Journal ArticleDOI
Maternal low‐protein diet affects bone mass and mineral metabolism in suckling rats
TL;DR: The results showed that protein-restricted diet given to mothers during late pregnancy and early post-natal periods induced changes in body weight, skeletal growth and bone metabolism in their offspring.