Journal ArticleDOI
Relation of Serum Lipoprotein Levels and Systolk Blood Pressure to Early Atherosclerosis; The Bogalusa Heart Study
W P Newman,David S. Freedman,A W Voors,P D Gen,S R Srinivasan,J L Crasanta,Williamson Gd,L S Webber,G S Bersison +8 more
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TLDR
The results document the importance of risk-factor levels to early anatomical changes in the aorta and coronary arteries and suggest that a rational approach to the prevention of cardiovascular disease should begin early in life.Abstract:
We assessed the relation of risk factors for cardiovascular disease to early atherosclerotic lesions in the aorta and coronary arteries in 35 persons (mean age at death, 18 years). Aortic involvement with fatty streaks was greater in blacks than in whites (37 vs. 17 percent, P less than 0.01). However, aortic fatty streaks were strongly related to antemortem levels of both total and low-density lipoprotein cholesterol (r = 0.67, P less than 0.0001 for each association), independently of race, sex, and age, and were inversely correlated with the ratio of high-density lipoprotein cholesterol to low-density plus very-low-density lipoprotein cholesterol (r = -0.35, P = 0.06). Coronary-artery fatty streaks were correlated with very-low-density lipoprotein cholesterol (r = 0.41, P = 0.04). Mean systolic blood-pressure levels also tended to be higher in the four subjects with coronary-artery fibrous plaques than in those without them: 112 mm Hg as compared with 104 (P = 0.09). These results document the importance of risk-factor levels to early anatomical changes in the aorta and coronary arteries. The progression of fatty streaks to fibrous plaques is uncertain, but these data suggest that a rational approach to the prevention of cardiovascular disease should begin early in life.read more
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Health complaints, stress, and distress: exploring the central role of negative affectivity.
David Watson,James W. Pennebaker +1 more
TL;DR: Results demonstrate the importance of including different types of health measures in health psychology research, and indicate that self-report health measures reflect a pervasive mood disposition of negative affectivity (NA), which will act as a general nuisance factor in health research.
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A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association.
H. C. Stary,A. B. Chandler,S. Glagov,John R. Guyton,W Insull,M. E. Rosenfeld,S A Schaffer,C. J. Schwartz,W. D. Wagner,R. W. Wissler +9 more
TL;DR: The compositions of lesion types that precede and that may initiate the development of advanced atherosclerotic lesions are described and the possible mechanisms of their development are reviewed.
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Lipid Screening and Cardiovascular Health in Childhood
TL;DR: The need for prevention of cardiovascular disease by following Dietary Guidelines for Americans and increasing physical activity is reemphasized and the need for pharmacologic agents and indications for treating dyslipidemia in children are reviewed.
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Outcomes of a Field Trial to Improve Children's Dietary Patterns and Physical Activity: The Child and Adolescent Trial for Cardiovascular Health (CATCH)
Russell V. Luepker,Cheryl L. Perry,Sonja M. McKinlay,Philip R. Nader,Guy S. Parcel,Elaine J. Stone,Larry S. Webber,John P. Elder,Henry A. Feldman,Carolyn C. Johnson,Steven H. Kelder,Margaret Wu +11 more
TL;DR: The CATCH intervention was able to modify the fat content of school lunches, increase moderate-to-vigorous physical activity in PE, and improve eating and physical activity behaviors in children during 3 school years.
Journal ArticleDOI
Cardiovascular Health in Childhood A Statement for Health Professionals From the Committee on Atherosclerosis, Hypertension, and Obesity in the Young (AHOY) of the Council on Cardiovascular Disease in the Young, American Heart Association
Christine L. Williams,Laura L. Hayman,Stephen R. Daniels,Thomas N. Robinson,Julia Steinberger,Stephen M. Paridon,Terry L. Bazzarre +6 more
TL;DR: In this paper, the authors provide strategies for promoting cardiovascular health that can be integrated into the comprehensive pediatric care of children, including physical activity, obesity, insulin resistance and type II diabetes mellitus, hypertension, high blood cholesterol, and cigarette smoking.