Research progress of circRNAs in chemotherapy resistance of digestive system neoplasms
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This article is published in World Chinese Journal of Digestology.The article was published on 2021-11-08 and is currently open access. It has received 0 citations till now.read more
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Circ_0003998 enhances doxorubicin resistance in hepatocellular carcinoma by regulating miR-218-5p/EIF5A2 pathway
TL;DR: The involvement of circular RNAs (circRNAs) in chemoresistance of tumors has been identified in this article, where the authors investigated the role and the underlying mechanism of circRNAs in doxorubicin (DOX) resistance in hepatocellular carcinoma (HCC).
Journal ArticleDOI
Depletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis.
TL;DR: In this paper, the role of hsa_circ_0000144 in oxaliplatin (OXA) resistance of GC cells was explored, which showed that hsa-circ-0000144 sponged miR-502-5p to positively regulate ADAM9 expression.
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Circ_0031242 Silencing Mitigates the Progression and Drug Resistance in DDP-Resistant Hepatoma Cells by the miR-924/POU3F2 Axis
TL;DR: In this article, the levels of circ(0031242, miR-924 and POU class 3 homeobox 2 (POU3F2) were detected by quantitative real-time polymerase chain reaction (qRT-PCR) or Western blot analysis.
Journal ArticleDOI
Regulation of Formation, Stemness and Therapeutic Resistance of Cancer Stem Cells
TL;DR: In this article, the authors discuss the mechanisms that orchestrate the characteristic of CSCs by the three elements and potential therapeutic strategies and summarize how several key regulatory factors function in the regulation of not only the formation and stemness maintenance, but also the therapeutic resistance of cancer stem cells.
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Circular RNA circHECTD1 prevents Diosbulbin-B-sensitivity via miR-137/PBX3 axis in gastric cancer
TL;DR: CircHECTD1 served as an oncogene by a novel miR-137/PBX3 axis, which might supply an underlying biomarker for the diagnosis and prognosis of GC management.