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Wei-Qiang Gao
Researcher at Shanghai Jiao Tong University
Publications - Â 223
Citations - Â 11045
Wei-Qiang Gao is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 49, co-authored 202 publications receiving 9693 citations. Previous affiliations of Wei-Qiang Gao include Columbia University & Rockefeller University.
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Patent
Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
Kevin P. Baker,Maureen Beresini,Laura DeForge,Luc Desnoyers,Ellen Filvaroff,Wei-Qiang Gao,Mary E. Gerritsen,Audrey Goddard,Paul J. Godowski,Austin L. Gurney,Steven Sherwood,Victoria Smith,Timothy A. Stewart,Daniel Tumas,Colin K. Watanabe,William I. Wood,Zemin Zhang +16 more
TL;DR: In this paper, the present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polyptides, and vectors and host cells comprising those nucleic amino acid sequences.
Journal ArticleDOI
Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears.
J L Zheng,Wei-Qiang Gao +1 more
TL;DR: It is reported here that overexpression of Math1, a mouse homolog of the Drosophila gene atonal, in postnatal rat cochlear explant cultures resulted in extra hair cells, and immature postnatal mammalian inner ears retained the competence to generate new hair cells.
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Generation of a prostate from a single adult stem cell
TL;DR: The data establish that single cells in the adult mouse prostate with multipotent, self-renewal capacity are defined by a Lin-Sca-1+CD133+CD44+CD117+ phenotype, and demonstrate that a single stem cell defined by the phenotype can generate a prostate after transplantation in vivo.
Journal ArticleDOI
Two-Amino Acid Molecular Switch in an Epithelial Morphogen That Regulates Binding to Two Distinct Receptors
Minhong Yan,Li-Chong Wang,Sarah G. Hymowitz,Sarah Schilbach,James Lee,Audrey Goddard,Abraham M. de Vos,Wei-Qiang Gao,Vishva M. Dixit +8 more
TL;DR: In situ binding and organ culture studies indicate that Eda-A1 and EDA-A2 are differentially expressed and play a role in epidermal morphogenesis.
Journal ArticleDOI
Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy.
Yuting Sun,Bu-Er Wang,Kevin G. Leong,Peng Yue,Li Li,Suchit Jhunjhunwala,Darrell Chen,Kyounghee Seo,Zora Modrusan,Wei-Qiang Gao,Jeffrey Settleman,Leisa Johnson +11 more
TL;DR: It is shown for the first time that androgen deprivation induces EMT in both normal prostate and prostate cancer, revealing a potentially important consequence of a standard-of-care treatment for prostate cancer.