Journal ArticleDOI
Room-Temperature Palladium-Catalyzed Amination of Aryl Bromides and Chlorides and Extended Scope of Aromatic C−N Bond Formation with a Commercial Ligand
TLDR
The reactions of aryl bromides with amines occurs at room temperature when using Pd(0) and P(t-Bu)(3) in a 1:1 ratio, and the reactions ofAryl chlorides occur atRoom temperature or 70 degrees C.Abstract:
The reactions of aryl bromides with amines occurs at room temperature when using Pd(0) and P(t-Bu)(3) in a 1:1 ratio, and the reactions of aryl chlorides occur at room temperature or 70 degrees C. The arylation of indoles and the new arylation of carbamates also occur when using P(t-Bu)(3) as ligand.read more
Citations
More filters
Journal ArticleDOI
Advances in non-metallocene olefin polymerization catalysis.
TL;DR: The graph below shows the progression of monoanionic and non-monoanionic ligands through the history of synthesis, as well as some of the properties that have been identified since the discovery of R-Diimine.
Journal ArticleDOI
Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
TL;DR: This Review attempts to trace the historical origin of these powerful reactions, and outline the developments from the seminal discoveries leading to their eminent position as appreciated and applied today.
Journal ArticleDOI
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
TL;DR: An overview of Pd-catalyzed N-arylation reactions found in both basic and applied chemical research from 2008 to the present is provided.
Journal ArticleDOI
Evolution of a fourth generation catalyst for the amination and thioetherification of aryl halides.
TL;DR: The conceptual basis and utility of the latest, "fourth-generation" palladium catalyst for the coupling of amines and related reagents with aryl halides is described and the effects of electronic properties on C-C and C-N bond-forming reductive elimination are similar.
Journal ArticleDOI
Synthesis and functionalization of indoles through palladium-catalyzed reactions
Sandro Cacchi,Giancarlo Fabrizi +1 more
TL;DR: P palladium-catalyzed synthesis can provide access to fine chemicals, agrochemical and pharmaceutical intermediates, and active ingredients in fewer steps and with less waste than classical.
References
More filters
Journal ArticleDOI
Rational Development of Practical Catalysts for Aromatic Carbon−Nitrogen Bond Formation
Journal ArticleDOI
Carbon−Heteroatom Bond-Forming Reductive Eliminations of Amines, Ethers, and Sulfides
Journal ArticleDOI
A Simple Catalytic Method for the Conversion of Aryl Bromides to Arylamines
TL;DR: In this paper, a facile and general catalytic method for the conversion of aryl bromides to arylamines was developed, which works well for inter- and intramolecular processes.
Journal ArticleDOI
A Highly Active Catalyst for Palladium-Catalyzed Cross-Coupling Reactions: Room-Temperature Suzuki Couplings and Amination of Unactivated Aryl Chlorides
Journal ArticleDOI
Palladium-catalyzed synthesis of arylamines from aryl halides. Mechanistic studies lead to coupling in the absence of tin reagents
Janis Louie,John F. Hartwig +1 more
TL;DR: In this paper, the reaction of aryl halides with secondary amines in the presence of silylamide base and tri- o -tolyphopshine palladium complexes gives arylamine products.