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Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis

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TLDR
Sedentary time is associated with an increased risk of diabetes, cardiovascular disease and cardiovascular and all-cause mortality; the strength of the association is most consistent for diabetes.
Abstract
Aims/hypothesis Sedentary (sitting) behaviours are ubiquitous in modern society. We conducted a systematic review and meta-analysis to examine the association of sedentary time with diabetes, cardiovascular disease and cardiovascular and all-cause mortality.

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Sedentary Time and Its Association With Risk for Disease Incidence, Mortality, and Hospitalization in Adults: A Systematic Review and Meta-analysis

TL;DR: This meta-analysis quantitatively evaluated the association between sedentary time and health outcomes independent of physical activity participation among adult populations to encompass the range of outcomes associated with sedentary behaviors among different populations or settings and variations in the operational definition of leisure-time sedentary behavior.
Journal Article

Sedentary Time and Its Association With Risk for Disease Incidence, Mortality, and Hospitalization in Adults

TL;DR: In this article, a systematic review and meta-analysis evaluated the association between physical activity and risk for disease and illness, and found that physical activity has many health-enhancing benefits, but it may not be enough to reduce the risk for diseases and illnesses.
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Plea for routinely presenting prediction intervals in meta-analysis.

TL;DR: The prediction interval reflects the variation in treatment effects over different settings, including what effect is to be expected in future patients, such as the patients that a clinician is interested to treat, in meta-analyses.
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Sedentary Behavior and Health Outcomes: An Overview of Systematic Reviews

TL;DR: It is shown that sedentary behavior may be an important determinant of health, independently of physical activity, however, the relationship is complex because it depends on the type of sedentarybehavior and the age group studied.
References
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Journal ArticleDOI

Meta-analysis of observational studies in epidemiology - A proposal for reporting

TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI

The Strengthening the Reporting of Observational Studies in Epidemiology [STROBE] statement: guidelines for reporting observational studies

TL;DR: The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) initiative developed recommendations on what should be included in an accurate and complete report of an observational study, resulting in a checklist of 22 items (the STROBE statement) that relate to the title, abstract, introduction, methods, results, and discussion sections of articles.
Journal ArticleDOI

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies

TL;DR: The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Initiative developed recommendations on what should be included in an accurate and complete report of an observational study, resulting in a checklist of 22 items that relate to the title, abstract, introduction, methods, results, and discussion sections of articles.
Journal ArticleDOI

Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis.

TL;DR: In this paper, a rank-based data augmentation technique is proposed for estimating the number of missing studies that might exist in a meta-analysis and the effect that these studies might have had on its outcome.
Journal ArticleDOI

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies

TL;DR: The STROBE Statement is a checklist of items that should be addressed in articles reporting on the 3 main study designs of analytical epidemiology: cohort, casecontrol, and cross-sectional studies; these recommendations are not prescriptions for designing or conducting studies.
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