Self‐perpetuating ring chromosomes in two human tumours
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This article is published in Hereditas.The article was published on 2010-07-09 and is currently open access. It has received 50 citations till now. The article focuses on the topics: Ring chromosome.read more
Citations
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On the biological alkylating agents
TL;DR: Pour lui, le poison devient un instrument qui dissocie and analyse les phenomenes les plus delicats of the machine vivante, and, en etudiant attentivement le mecanisme de the mort, il s'instruit par voie indirecte sur le me canisme physiologique de the vie.
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The structure and dynamics of ring chromosomes in human neoplastic and non-neoplastic cells.
David Gisselsson,Mattias Höglund,Fredrik Mertens,Börje Johansson,P. Dal Cin,H. Van den Berghe,William C. Earnshaw,Felix Mitelman,Nils Mandahl +8 more
TL;DR: It is concluded that it is not only the ring structure per se or the neoplastic nature of the host cell that determines ring instability, but probably also the functional role of the genes carried in the ring.
Journal ArticleDOI
Ring Chromosomes in Human Beings
Hsi-Chang Wang,Hsi-Chang Wang,John Melnyk,John Melnyk,Lyle T. Mcdonald,Lyle T. Mcdonald,Irene A. Uchida,Irene A. Uchida,David H. Carr,Benjamin Goldberg +9 more
TL;DR: A ring chromosome is found in two children, a different chromosome being involved in each case, and there are no apparent signs of neoplastic disease in either patient.
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Cytological studies of tumors, XXVII. The chromosomes of thirty human tumors.
TL;DR: The chromosome conditions were investigated in thirty cases of primary human tumors in two types of material, solid and effusion, by the use of the water-pretreatment squash method, suggesting that the genetic pattern which is closely correlated with the property of the tumor may not be identical in each tumor, even though they originated from the same organ.
References
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The Production of Homozygous Deficient Tissues with Mutant Characteristics by Means of the Aberrant Mitotic Behavior of Ring-Shaped Chromosomes.
TL;DR: This lengthy article stemmed from McClintock's discovery of ring chromosomes in 1932 and research she conducted on the gene bm1, or brown midrib, after returning to the University of Missouri in 1938.
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The chromosomes of two highly malignant human tumours.
Ulla Ising,Albert Levan +1 more
TL;DR: The variation in nuclear size, often commented upon in pathological diagnoses, finds an explanation in the chromosome number variation typical of tumours, the increased nuclear size in tumours corresponding to an increased average chromosome number, and the multinuclearity and lobation of nuclei in tumour being often a consequence of so-called c-mitotic processes.
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An Analysis of Chromosome Structure and Behavior with the Aid of X-Ray Induced Rearrangements.
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The nature of closedX-chromosomes inDrosophila melanogaster
Jack Schultz,D. G. Catcheside +1 more
TL;DR: The two closedX-chromosomes of Drosophila melanogaster are shown to be duplicated at their bobbed, deficient at their yellow ends, in agreement with their origin as the result of translocations between the attachedX’s carried by their mothers.