Journal ArticleDOI
Serum Albumin and Nutritional Status
R. Armour Forse,Harry M. Shizgal +1 more
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The data indicate that serum albumin is a valid measure of nutritional state for epidemiological surveys, however, due to the low sensitivity and specificity it is a poor parameter for evaluating the individual patient's nutritional state.Abstract:
Serum albumin concentration is frequently used to define nutritional status. To validate this relationship, 161 body composition studies were performed on 102 patients simultaneously with protein electrophoresis. The body cell mass represented by the exchangeable potassium to total body water ratio correlated significantly (p < 0.001) with the serum albumin concentration (r = 0.59) and significantly (p < 0.001) to total protein (r = 0.59). However, in both cases the 95% confidence limits about the regression were wide. In 24 of 54 patients (44%) with a normal nutritional state, as defined by body composition, the serum albumin was abnormal. In 12 of 107 (11.2%) patients with malnutrition, the serum albumin was normal. Patients with more than one study were divided into 3 groups depending on the changes in their nutritional state as defined by their body composition. Serum albumin did not consistently reflect the significant body compositional changes observed. The data indicate that serum albumin is a valid measure of nutritional state for epidemiological surveys. However, due to the low sensitivity and specificity it is a poor parameter for evaluating the individual patient's nutritional state.read more
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Hepatic proteins and nutrition assessment
TL;DR: Compelling evidence suggests that serum hepatic protein levels correlate with morbidity and mortality, and they help identify those who are the most likely to develop malnutrition, even if well nourished prior to trauma or the onset of illness.
Journal ArticleDOI
Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in out-patients with COPD
Mariëlle P.K.J. Engelen,Annemie M. W. J. Schols,W. C. Baken,Geertjan Wesseling,E. F. M. Wouters +4 more
TL;DR: It is concluded that a substantial number of COPD out-patients suffer from nutritional depletion, preferentially affecting peripheral skeletal muscle function.
Journal ArticleDOI
Assessment of protein energy malnutrition in older persons, Part II: Laboratory evaluation.
M.Louay Omran,John E. Morley +1 more
TL;DR: Many of the biochemical parameters used in nutritional assessment and their relation to morbidity and mortality, with a special focus on normal changes seen with aging are reviewed.
Journal ArticleDOI
Reviews: The Role of Albumin in Human Physiology and Pathophysiology, Part III: Albumin and Disease States
TL;DR: The serum albumin level is one of several clinical parameters of the status of general health that results from alterations in the catabolic or anabolic rates, losses of albumin, or redistribution between the various fluid compartments of the body.
Journal ArticleDOI
Serum albumin is associated with skeletal muscle in elderly men and women.
TL;DR: In this article, the authors examined associations of serum albumin with age and found that decreases with age in albumin concentrations are associated with muscle loss (sarcopenia) in the elderly.
References
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