Site of Heart Block in Acute Myocardial Infarction
Kenneth M. Rosen,Henry S. Loeb,Ruben Chuquimia,M. Ziad Sinno,Shahbudin H. Rahimtoola,Rolf M. Gunnar +5 more
TLDR
Electrophysiologic observations coupled with previous clinical, anatomic, and pathologic findings suggest that the heart block in DMI is usually due to an ischemic lesion of the A-V node, whileheart block in AMI is due to necrosis involving both bundle branches.Abstract:
Bundle of His electrograms were recorded in eight patients with acute myocardial infarction and heart block. Three patients with diaphragmatic myocardial infarction (DMI) and one with subendocardial infarction were characterized by slowing or block above the bundle of His and A-V junctional escape rhythms during periods of advanced or complete block. An additional patient with DMI had block in the His bundle itself. Intraventricular conduction in the above patients was characterized by normal H-Q intervals (35 to 60 msec) and absence of widened QRS. In contrast, three patients with anterior infarction (AMI) manifested complete block below the bundle of His and idioventricular escape. P-H intervals were normal (80 to 140 msec) and A-V conduction was considered unaffected. Our electrophysiologic observations coupled with previous clinical, anatomic, and pathologic findings suggest that the heart block in DMI is usually due to an ischemic lesion of the A-V node, while heart block in AMI is due to necrosis in...read more
Citations
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Journal ArticleDOI
Sites of Congenital and Surgical Heart Block as Defined by His Bundle Electrocardiography
TL;DR: It is suggested that recording of H potentials is useful in the evaluation of children with complete atrioventricular block afterCatheter recordings of His bundle electrograms in patients with congenital heart block and in two with surgical heart block.
Book ChapterDOI
Chronotropic and Dromotropic Effects of Adenosine
TL;DR: It is of more than historic interest that the A-V block observed in the guinea pig heart first drew the attention of Drury and Szent-Gyorgyi to the physiologial activity of the nucleic acid derivatives.
Journal ArticleDOI
The Contribution of His Bundle Recording to the Understanding of Cardiac Conduction in Man
TL;DR: With proper catheter positioning, amplffication and frequency filtering, the His bundle (H) potential can reliably be recorded as a bior triphasic deflection between the atrial and ventricular electrograms.
Journal ArticleDOI
Chronic heart block in adults. Clinical and electrophysiological observations.
TL;DR: Although symptoms related to bradycardia occurred in all groups, syncope was significantly more common with block distal to H, and neither ventricular rate or QRS duration could be used as an absolute guide to the site of block.
Journal ArticleDOI
His Bundle Electrogram A Critical Appraisal of its Uses and Limitations
Scherlac Bj,Samet P,Helfant Rh +2 more
TL;DR: The His bundle electrogram, in conjunction with the surface electrocardiogram, has provided a more accurate means of localizing the site of conduction abnormality in patients with various forms of heart block.
References
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Journal ArticleDOI
Catheter Technique for Recording His Bundle Activity in Man
Benjamin J. Scherlag,Sun H. Lau,Richard H. Helfant,Walter D. Berkowitz,Emanuel Stein,Anthony N. Damato +5 more
TL;DR: The use of this recording technique in man will facilitate diagnostic interpretation of the electrocardiogram and can be used in various investigations of atrioventricular and intraventricular conduction in man.
Journal ArticleDOI
Blood Supply of the Human Interventricular Septum
Thomas N. James,George E. Burch +1 more
TL;DR: The blood supply of the interventricular septum has been studied in 43 normal human hearts, from patients dying of noncardiac causes, and its clinical importance is discussed.
Journal ArticleDOI
Anatomy of the Coronary Arteries in Health and Disease
TL;DR: The presentation was oriented to stress topics of special value to the physician dealing with patients having heart disease.
Journal ArticleDOI
A study of heart block in man using His bundle recordings.
Anthony N. Damato,Sun H. Lau,Richard H. Helfant,Emanuel Stein,Robert D. Patton,Benjamin J. Scherlag,Walter D. Berkowitz +6 more
TL;DR: The technique of recording His bundle electrograms in man by a tripolar electrode catheter was applied in a study of patients with first, second, and third-degree heart block and the enhancement of A-V conduction due to isoproterenol was qualitatively similar in the three forms of first-degree block.
Journal ArticleDOI
Atrioventricular Block, Type II (Mobitz)—Its Nature and Clinical Significance
Richard Langendorf,Alfred Pick +1 more
TL;DR: The observations of Mahaim,4 Yater and associates,5 Lev and Unger,6 and Lenegre and Moreau7 strongly suggest that bilateral bundle-branch block may be the usual anatomic substrate of type II A-V block.
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