Journal ArticleDOI
Size-dependent separation of proteins denatured in SDS by capillary electrophoresis using a replaceable sieving matrix
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TLDR
The calculated resolution at half-peak height was such that proteins that differed by as little as 4% in molecular weight would be resolved, and the integrated peak areas at 215 nm were linearly proportional to the mass of the protein injected.About:
This article is published in Analytical Biochemistry.The article was published on 1993-07-01. It has received 86 citations till now. The article focuses on the topics: Gel electrophoresis & Capillary electrophoresis.read more
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Protein sizing on a microchip.
TL;DR: A microfabricated analytical device on a glass chip that performs a protein sizing assay, by integrating the required separation, staining, virtual destaining, and detection steps is developed, and a universal noncovalent fluorescent labeling method is obtained.
Patent
Method for comparing copy number of nucleic acid sequences
TL;DR: In this paper, a method for comparing and identifying differences in nucleic acid sequences using a plurality of sequence specific recognition reagents (i.e., probes comprising a nuclei acid complementary to a nucleic amino acid sequence in collections to be compared) bound to a solid surface is presented.
Journal ArticleDOI
Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications
TL;DR: These articles sum up the existing strategies for method development in CE, especially in the search for generally accepted concepts, but also looking for new, promising reagents and ideas.
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