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Journal ArticleDOI

Sodium metabisulfite--a marker for cosmetic allergy?

TLDR
It is hypothesize that a reaction to sodium metabisulfite may be a marker for sulfite allergy in cosmetics and might account for some of the unexplained positives in previous reports.
Abstract
A 45-year-old woman developed dermatitis of the face after she applied a cosmetic package comprising day and night creams. Patch tests were performed with the British Contact Dermatitis Society (BCDS) standard, bases + preservatives, and cosmetic series in addition to samples of both creams and the individual constituents. She had positive tests to both cosmetic creams, sodium sulfite from the manufacturer's samples (5% white soft paraffin (WSP)), and sodium metabisulfite (1% pet) in our bases + preservatives battery. Sodium sulfite is a constituent of both cosmetic creams. We assume that the positive test to sodium metabisulfite is a cross-reaction. We hypothesize that a reaction to sodium metabisulfite may be a marker for sulfite allergy in cosmetics and might account for some of the unexplained positives in previous reports.

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Citations
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Journal ArticleDOI

Clinical effects of sulphite additives.

TL;DR: Physicians should be aware of the range of clinical manifestations of sulphite sensitivity, as well as the potential sources of exposure, and minor modifications to diet or behaviour lead to excellent clinical outcomes for sulphite‐sensitive individuals.
Journal ArticleDOI

Adverse reactions to the sulphite additives.

TL;DR: Most studies report a prevalence of sulphite sensitivity of 3 to 10% among asthmatic subjects who ingest these additives, but steroid-dependent asthmatics, those with marked airway hyperresponsiveness, and children with chronic asthma, appear to be at greater risk.
Journal ArticleDOI

Contact dermatitis: allergic and irritant.

TL;DR: Clinical assessment of a patient with facial contact dermatitis and the mechanisms of both ICD and ACD are focused on, and suggestions are made regarding the management of patients with proven ICD or ACD of the face.
Journal ArticleDOI

Allergic contact dermatitis caused by sodium metabisulfite: a challenging allergen. A case series and literature review

TL;DR: Sulfites, preservatives and antioxidants used in the cosmetic, pharmaceutical and food industry are contact allergens whose relevance seems to be difficult to establish.
Journal ArticleDOI

Allergic and Immunologic Reactions to Food Additives

TL;DR: All of the food additives which were approved to consume in EU and find out how common and serious allergic reactions come into existence following the consuming of food additives are overviewed.
References
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Journal ArticleDOI

Sulfite contact allergy

TL;DR: In the last 2 years, 2,894 consecutive eczematous patients were patch tested with sodium metabisulfite 1% pet, and positive reactions were elicited in 50 subjects, with only 5 out of 43 non‐occupational cases was the positive reaction considered relevant.
Journal ArticleDOI

Consecutive patch testing with sodium sulfite in eczema patients

TL;DR: This data presents the data from 1762 consecutive patients tested with sodium sulfite 1% pet for allergic contact dermatitis over a 25-year period and indicates that the prevalence of Type N allergic reactions to Sodium sulfite is unknown.
Journal ArticleDOI

Type IV hypersensitivity to sodium metabisulfite in local anaesthetic

TL;DR: A patient received an anaesthetic injection for a biopsy of a suspected basal cell carcinoma on the left forearm that consisted of, among other constituents, lidocaine 2% with adrenaline, and experienced a burning sensation, erythema and swelling at site of the injection after 48 hr.
Journal Article

Sulfite-induced urticaria.

TL;DR: A case of urticaria induced by metabisulfites is presented, unable to identify a pathogenic mechanism, in a nonasthmatic patient without asthma.
Journal ArticleDOI

Concomitant sensitivity to sodium metabisulfite and clobetasone butyrate in Trimovate cream.

D. A. Harrison, +1 more
- 01 May 2002 - 
TL;DR: A 75-year-old-woman who was prescribed TrimovateA (GlaxoSmith Kline, ) cream for vulval soreness developed a worsening of symptoms and, after 10days, a more widespread, florid, eczematous eruption involving particularly the face and eyelids but also the back and upper arms.
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