Book ChapterDOI
Some Aspects of Immunologic Studies in Schizophrenia
G. I. Kolyaskina,T. P. Sekirina,A. A. Zozulya,S. G. Kushner,M. Ya. Zuzulkovskaya,L. I. Abramova +5 more
- pp 285-294
TLDR
In discussions about the pathogenesis of schizophrenia, immunopathological processes have been noted among the possible initial or triggering steps of this disease.Abstract:
In discussions about the pathogenesis of schizophrenia, immunopathological processes have been noted among the possible initial or triggering steps of this disease.read more
Citations
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Journal ArticleDOI
Meta-Analysis of Lymphocytes in Schizophrenia: Clinical Status and Antipsychotic Effects
TL;DR: Blood lymphocyte abnormalities in drug-naïve first-episode psychosis suggest an effect that may be independent of antipsychotic medications, while some parameters (CD4/CD8) may be state markers for acute exacerbations of psychosis, others may be trait markers; however, more longitudinal studies are needed.
Journal ArticleDOI
Lymphocyte subsets in schizophrenic disorders: relationship with clinical, neuromorphological and treatment variables
Cinzia Masserini,Antonio Vita,Roberto Basile,Raffaele Morselli,Paolo Boato,Cinzia Peruzzi,Luigi Pugnetti,Pasquale Ferrante,Carlo Lorenzo Cazzullo +8 more
TL;DR: Peripheral blood lymphocyte subsets and serum immunoglobulin levels were assessed in 42 patients and 37 healthy controls and the drug naive spectrum disorder patients showed an increase of absolute number of lymphocytes, while the drug treated spectrum group showed a increase of B lymphocytes.
Journal ArticleDOI
Increased levels of CD8+ and CD4 + 45RA + lymphocytes in schizophrenic patients
Carlo Lorenzo Cazzullo,Marina Saresella,K. Roda,Maria Gaetana Calvo,Paolo Bertrando,S. Doria,Mario Clerici,A. Salvaggio,Pasquale Ferrante +8 more
TL;DR: The present data confirm the presence of immunological abnormalities in schizophrenic patients and suggest a possible role of environmental factors in the triggering of an autoimmune pathogenic mechanism.
Journal ArticleDOI
Abnormal distributions of T-lymphocyte subsets in the cerebrospinal fluid of patients with acute schizophrenia.
TL;DR: As compared to the distribution of T cell subsets in the CSF from non-psychotic controls, the schizophrenic patients displayed both abnormally high and abnormally low frequencies of CD4+ and/or CD8+ cells.
Book ChapterDOI
Stress and Immunity in Humans: Modifying Variables
TL;DR: This chapter focuses on the variables that are capable of modulating the effects of stressors on the human immune system.
References
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Journal Article
Aspects of humoral and cellular immunity in schizophrenia.
Book
Research on the viral hypothesis of mental disorders
TL;DR: This work will concern you to try reading research on the viral hypothesis of mental disorders advances in biological psychiatry hardcover as one of the reading material to finish quickly.
Journal ArticleDOI
Cell interactions in the immune response: effect of humoral factor released from bone marrow cells on the quantity of mature antibody producers in culture of immune lymph node cells.
TL;DR: It was shown that the increased numbers of antibody-producing cells, causing the stimulation effect, appear in immune lymph node cell population under the influence of a nondialyzable humoral factor released by intact bone marrow cells.
Journal ArticleDOI
Antithymic immune factor in schizophrenia. A World Health Organization study
G. Koliaskina,M. Tsutsulkovskaya,I. Domashneva,T. Maznina,P. Kielholz,M. Gastpar,WilliamE. Bunney,O. Rafaelsen,J. Heltberg,A. Coppen,H. Hippius,B. Hoecherl,F. Vartanian +12 more
TL;DR: Six WHO Collaborating Centre took part in the study of the antithymic activity of blood sera of patients suffering from schizophrenia.