Journal ArticleDOI
Stress and antibody response in rats.
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This article is published in International Archives of Allergy and Immunology.The article was published on 1969-01-01. It has received 224 citations till now.read more
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The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interactions.
Bruce S. McEwen,Christine A. Biron,Kenneth W. Brunson,Karen Bulloch,William H. Chambers,Firdaus S. Dhabhar,Ronald H. Goldfarb,Richard P. Kitson,Andrew H. Miller,Robert L. Spencer,Jay M. Weiss +10 more
TL;DR: This work presents a meta-anatomy of the adrenal gland and its role in the development and management of disease and urges further investigation into the role of “cell reprograming” and “reconcretization” in the course of disease progression.
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Psychosocial modifiers of immunocompetence in medical students.
Janice K. Kiecolt-Glaser,Warren Garner,Carl E. Speicher,Gerald M. Penn,Jane E. Holliday,Ronald Glaser +5 more
TL;DR: Blood was drawn twice from 75 first‐year medical students, with a baseline sample taken one month before their final examinations and a stress sample drawn on the first day of final examinations to address the effects of a naturally occurring stressor on components of the immune response.
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Enhancing versus suppressive effects of stress hormones on skin immune function
TL;DR: The results suggest a role for adrenal stress hormones as endogenous immunoenhancing agents and show that hormones released during an acute stress response may help prepare the immune system for potential challenges for which stress perception by the brain may serve as an early warning signal.
Journal ArticleDOI
Opioid peptides mediate the suppressive effect of stress on natural killer cell cytotoxicity
TL;DR: The cytotoxic activity of natural killer cells was investigated in rats subjected to one of two inescapable footshock stress paradigms, both of which induce analgesia, but only one via activation of opioid mechanisms.
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Stress-induced modulation of the immune response
TL;DR: Both the blastogenic activity of concanavalin A or lipopolysaccharide and the ability of immune lymphocytes to lyse P815 target cells showed the same patterns of immunosuppression and enhancement.