Successful repeated thrombolysis in a patient with HeartWare thrombosis - the importance of Doppler flow pattern.
Lech Paluszkiewicz,Michiel Morshuis,K Hakim-Meibodi,Stephan Ensminger,Jan Gummert +4 more
- Vol. 11, Iss: 4, pp 428-431
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TLDR
A patient after implantation of a left ventricular assist device (HeartWare) for destination therapy complicated by recurrent thrombosis of the device is presented.Abstract:
Here we present a patient after implantation of a left ventricular assist device (HeartWare) for destination therapy complicated by recurrent thrombosis of the device. At 14 months after implantation, the patient presented with a pump thrombosis after an INR incompliance period. A surgical pump exchange was performed and the patient recovered uneventfully. Five months later a pump thrombosis occurred again, and the patient refused surgery. Systemic thrombolysis was carried out this time. Three and 6 months later the same clinical picture was presented again, and repeat thrombolysis was performed successfully. The patient was discharged and has remained stable since, without any symptoms of thrombosis of the device.read more
Citations
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Journal ArticleDOI
Medical Management of Pump-Related Thrombosis in Patients with Continuous-Flow Left Ventricular Assist Devices: A Systematic Review and Meta-Analysis.
Geetanjali Dang,Narendranath Epperla,Vijayadershan Muppidi,Natasha Sahr,Amy Pan,Pippa Simpson,Lisa Baumann Kreuziger +6 more
TL;DR: A systematic review to evaluate the efficacy and complications associated with medical management of LVAD thrombosis found that Randomized clinical trials comparing thrombolytic and nonthrom bolytic treatment of LVadal assist devices are needed to establish the most effective and safe option for patients who are not surgical candidates.
Journal ArticleDOI
Conservative approaches for HeartWare ventricular assist device pump thrombosis may improve the outcome compared with immediate surgical approaches
TL;DR: This report showed the feasibility of several alternative conservative approaches combining medications, minimally invasive and interventional methods for patients with HeartWare pump thrombosis, and suggested the outcome may be better than immediate surgical pump exchange.
Journal ArticleDOI
Medical Therapy As Compared To Surgical Device Exchange for Left Ventricular Assist Device Thrombosis: A Systematic Review and Meta-Analysis.
Jessica G.Y. Luc,Vakhtang Tchantchaleishvili,Kevin Phan,Shannon M. Dunlay,Simon Maltais,John M. Stulak +5 more
TL;DR: Surgical pump exchange is superior to medical therapy with a higher success rate of pump thrombosis resolution, lower mortality rate, and lower recurrence rate.
Journal ArticleDOI
Mechanical circulatory support in heart failure.
TL;DR: An up-to-date overview of the current knowledge on the role of MCS in modern medicine is presented.
Dissertation
Tranzitorni signali visokog intenziteta u bolesnika s ugrađenim cirkulacijskim crpkama
TL;DR: Zatajenje srca sindrom je multifaktorske etiologije od kojeg boluje 1-2% odrasle populacije i odsutnost odgovarajuceg broja donora za transplantaciju.
References
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Journal ArticleDOI
Treatment of Thrombus Formation Associated With the MicroMed DeBakey VAD Using Recombinant Tissue Plasminogen Activator
Markus Rothenburger,Markus J. Wilhelm,Dieter Hammel,Christoph Schmidt,Tonny D.T. Tjan,Dirk Böcker,Hans H. Scheld,Christof Schmid +7 more
TL;DR: Rt-PA lysis is a very effective tool for thrombus-related pump dysfunction in patients with impeller pumps, which renders emergency surgical exchange unnecessary in most cases.
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Management of HeartWare left ventricular assist device thrombosis using intracavitary thrombolytics.
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HeartWare continuous-flow ventricular assist device thrombosis: the Bad Oeynhausen experience.
Journal ArticleDOI
Tenecteplase: a review of its pharmacology and therapeutic efficacy in patients with acute myocardial infarction.
Christopher J. Dunn,Karen L. Goa +1 more
TL;DR: Bolus tenecteplase is an effective thrombolytic agent, suitable for first-line use in patients with acute myocardial infarction with ST segment elevation, with comparable mortality after 1 year's follow-up.
Journal ArticleDOI
HeartMate II Ventricular Assist Device Thrombosis—An Echocardiographic Approach to Diagnosis: Can Doppler Evaluation of Flow Be Useful?
Lech Paluszkiewicz,Dilek Gürsoy,Sotirios Spiliopoulos,Günes Dogan,Stavros I Daliakopoulos,Magda Tenderich,Reiner Körfer,Gero Tenderich +7 more
TL;DR: In this paper, a 68-year-old man was admitted to the hospital 4 months after HeartMate II ventricular assist device implantation, because his clinical status had deteriorated and his levels of lactate dehydrogenase and free hemoglobin had increased.