J
Jan D. Schmitto
Researcher at Hannover Medical School
Publications - 320
Citations - 6911
Jan D. Schmitto is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Ventricular assist device & Heart failure. The author has an hindex of 38, co-authored 296 publications receiving 5560 citations. Previous affiliations of Jan D. Schmitto include Heart and Diabetes Center North Rhine-Westphalia & German Aerospace Center.
Papers
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Journal ArticleDOI
Altered Na+Currents in Atrial Fibrillation: Effects of Ranolazine on Arrhythmias and Contractility in Human Atrial Myocardium
Samuel Sossalla,Birte Kallmeyer,Stefan Wagner,Marek Mazur,Ulrike Maurer,Karl Toischer,Jan D. Schmitto,Ralf Seipelt,Friedrich A. Schöndube,Gerd Hasenfuss,Luiz Belardinelli,Lars S. Maier +11 more
TL;DR: Investigating changes in Na(+) currents in permanent (or chronic) atrial fibrillation and the effects of I(Na) inhibition using ranolazine (Ran) on arrhythmias and contractility in human atrial myocardium found antiarrhythmic effects and improved diastolic function.
Journal ArticleDOI
Minimally-invasive valve surgery.
TL;DR: The existing literature is reviewed and the current state-of-the-art of minimally-invasive valve operations is presented in this paper.
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Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts.
Luka Nicin,Wesley Abplanalp,Hannah Mellentin,Badder Kattih,Lukas Tombor,David John,Jan D. Schmitto,Jörg Heineke,Fabian Emrich,Mani Arsalan,Tomas Holubec,Thomas Walther,Andreas M. Zeiher,Stefanie Dimmeler +13 more
TL;DR: This poster presents a poster presented at the 2016 European Conference on Cardiovascular Regeneration and Cardiopulmonary Institute (ECAS) at the University of Heidelberg, Germany, on the topic of regenerative medicine and cardiothoracic surgery.
Journal ArticleDOI
Inhibition of Elevated Ca2+/Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium
Samuel Sossalla,Nina Fluschnik,Hanna Schotola,Katharina Ort,Stefan Neef,Timo Schulte,Katrin Wittköpper,André Renner,Jan D. Schmitto,Jan Gummert,Ali El-Armouche,Gerd Hasenfuss,Lars S. Maier +12 more
TL;DR: CaMKII inhibition acutely improves contractility in human HF where CaMKII&dgr; expression is increased, and appears to be a possible therapeutic option for patients with HF and merits further investigation.
Journal ArticleDOI
Fully Magnetically Levitated Left Ventricular Assist System for Treating Advanced HF: A Multicenter Study.
Ivan Netuka,Poornima Sood,Yuriy Pya,Daniel Zimpfer,Thomas Krabatsch,Jens Garbade,Vivek Rao,Michiel Morshuis,Silvana Marasco,Friedhelm Beyersdorf,Laura Damme,Jan D. Schmitto +11 more
TL;DR: The results show that the fully magnetically levitated centrifugal-flow chronic LVAS is safe, with high 30-day and 6-month survival rates, a favorable adverse event profile, and improved quality of life and functional status.